This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will leverage artificial intelligence methods and electronic health records to conduct pharmacoepidemiologic studies on adverse pediatric outcomes associated with maternal substance use during pregnancy and pediatric drug exposures. The goal is to develop a stakeholder-informed real-time pediatric...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to investigate the effects of maternal medication exposures on early life health outcomes in children. The $108,512.00 award to the University of Chicago, granted on Nov 22, 2025, will fund a three-part research effort: Building a high-quality registry of mother-child pairs by extracting additional phenotype...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $419,615 to Thomas Jefferson University to continue supporting two pediatric and maternal-fetal clinical pharmacology training slots. The 5-year program aims to train the next generation of drug development scientists to ensure innovation in therapeutics that transforms disease management. The...
This $190,163 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support the University of Utah's Pediatric Clinical Pharmacology Training Program. The goal of this program is to develop clinician and PhD-scientists as leaders in the field of pediatric and maternal clinical pharmacology research. The funding will provide training and experience in the methods...
This $153,252 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to develop strategies for identifying individuals at high risk for genetic diseases in order to enable earlier diagnosis and treatment. The award has two key aims: 1) Reevaluating guidelines for universal preconception carrier screening to improve uptake and include new actionable...
This $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to develop an early life phenotyping framework for very preterm infants. The research aims to create 'perinatal phenotypes' by integrating variables such as reason for preterm birth, intrapartum care, and neonatal presentation, and then determine how these phenotypes contribute to...
This $158,216 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support a longitudinal study on the effects of prenatal exposure to maternal incarceration on infant and toddler health and development. The research will analyze data from the "Birth Beyond Bars" study to assess the impact of environmental factors before and during maternal...
This federal Project Grant award for $1,332,733.00, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to understand the impact of preconception lifestyle factors, such as physical activity, diet, and sleep, on pregnancy outcomes. The award recipient, The Trustees of the University of Pennsylvania, will leverage the linkage between the National Health and...
This $2,146,691 Project Grant, awarded by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund a study on the effects of the prenatal RSV prefusion F protein-based (RSVpreF) vaccine on neonatal, lactation, and child health outcomes. The study will leverage electronic health record data and state immunization information systems across four large health systems to examine a cohort of up to...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will provide $102,168 to support a research study conducted by the University of California, San Francisco (UCSF). The study aims to evaluate the effects of state-level initiatives to reduce early-term elective deliveries (EEDS) on maternal and newborn outcomes, as well as disparities in these outcomes. The...
This $382,226 Project Grant from the Department of Health and Human Services' National Institutes of Health National Institute of Child Health and Human Development supports the development of a platform for uncovering new drug safety information through analysis of linked electronic health records. Vanderbilt University Medical Center will analyze 48,434 linked maternal and neonatal EHRs to apply a medication-wide association study and discover associations between maternal drug exposures and teratogenic health outcomes in newborns. This aims to systematically clarify cases of suspect drug safety in pregnancy, allowing clinicians to make more informed risk-benefit assessments when prescribing drugs of unclear teratogenic risk. The work supports the Child Health and Human Development Extramural Research program's goals of exploring health processes through laboratory and clinical research with human subjects.