This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will leverage artificial intelligence methods and electronic health records to conduct pharmacoepidemiologic studies on adverse pediatric outcomes associated with maternal substance use during pregnancy and pediatric drug exposures.
The goal is to develop a stakeholder-informed real-time pediatric pharmacovigilance system to monitor adverse drug reactions in children, with the expected outcome of a clinical decision support tool for early detection of these events. The $481,250 award to Vanderbilt University Medical Center (VUMC) will fund the project over a 2-year period from September 1, 2023 to August 31, 2025. This work builds upon VUMC's expertise in biomedical research, leveraging its large electronic health record database of mother-child dyads to investigate critical drug safety issues in the pediatric population.
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