Project Grant R21EY035492
Award Date
5/1/25
Completion Date
4/30/27
Dollars Obligated
$448K
Federal Agency
National Eye Institute
Federal Grant Program
93.867
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
This federal Project Grant award, totaling $366,399, was provided by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867). The grant supports a research project to investigate the role of the PAX6 transcription factors, Eyeless (Ey) and Twin of Eyeless (Toy), in specifying and patterning the Drosophila compound eye. The research aims to overcome limitations in understanding the individual and combined contributions of Ey and Toy to eye formation and patterning,...
This Project Grant award from the National Eye Institute (NEI), funding program CFDA 93.867 Vision Research, aims to define the genetic determinants of extraocular motor neuron subtype development and understand the impact of disrupting these factors. The research will be conducted by New York University (NYU) School of Medicine, with a total funding amount of $510,586 over the project period from June 1, 2024 to March 31, 2028. The key products and services to be delivered under this award...
This $1,789,542 federal Project Grant award from the National Eye Institute (NEI), under the CFDA 93.867 Vision Research program, supports a research project to study the role of modular super-enhancers in regulating gene expression during retinal development in mice and humans. The award aims to identify developmental stage- and cell type-specific promoter-super-enhancer interactions for key retinal transcription factor genes, which is critical for understanding the non-coding genome's...
The National Eye Institute (NEI) awarded a $543,037 Project Grant (CFDA 93.867 - Vision Research) to New York University School of Medicine to support research on the development and function of corneal lens-secreting cells. The funding will be used to: Investigate how cell type-specific gene expression in retinal cone and pigment cells, which contribute to corneal lens formation, is regulated by transcription factors and chromatin accessibility. Examine how the timing of cone and pigment cell...
This is a Project Grant award from the National Eye Institute (NEI), part of the National Institutes of Health (NIH), under the Vision Research program (CFDA 93.867). The $451,000 award supports research by the University of Texas Southwestern Medical Center to investigate the role of the FIC enzyme in regulating the unfolded protein response (UPR) in the mammalian retina. Specifically, the project aims to determine if FIC-mediated modification of the BIP protein can modulate UPR activation,...
This Project Grant award, valued at $154,332.00, was provided by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867). The funding supports research led by New York University to characterize the neural circuits underlying color vision in Drosophila, with the goal of identifying the molecular mechanisms that coordinate neuronal specification and synaptic partner matching during circuit assembly. Key activities under this award include: 1) conducting...
This federal Project Grant award R21EY036999, totaling $214,227.00, was provided by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867). The primary goal of the project is to utilize the chicken embryo model to decode the transcriptional regulation of the FOXE3 gene, which is critical for lens development. The research aims to identify the cis-regulatory elements and transcription factors that control FOXE3 gene expression in the developing lens, in...
This Project Grant award from the National Eye Institute (NEI), under the NEI Vision Research federal grant program (CFDA 93.867), supports research to investigate the transcriptional control mechanisms mediated by the small MAF transcription factors MAFG and MAFK, and their co-regulator NRF2, in lens development and their impact on the human cataract-linked transcription factor C-MAF. The $386,676 award, valid from January 1, 2025 to December 31, 2029, will enable the University of Delaware to:...
The University of Utah has been awarded a $423,500 Project Grant from the National Eye Institute (NEI) under the NIH's Vision Research program (CFDA 93.867) to study the role of microglia in the development of the optic stalk during early eye formation. The research aims to determine whether microglia, the resident immune cells of the central nervous system, participate in apoptotic cell elimination and tissue remodeling processes that are critical for normal closure of the optic fissure....
This $211,988 federal Project Grant awarded by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) supports research to investigate the neural mechanisms underlying orientation-dependent surround suppression in the visual cortex. The primary goal is to develop a detailed mechanistic circuit model explaining how orientation-dependent surround suppression is generated through feedback connections from higher visual areas to inhibitory interneurons in the primary visual...