Project Grant R21ES039102
- The National Institute on Aging awarded the University of New Mexico Health Sciences Center a project grant of $305,000 on September 1, 2026, to study micro(nano)plastic accumulation in the central nervous system and its effects on cerebrospinal fluid-mediated waste removal. The research advances quantification methods for micro(nano)plastics in human cerebrospinal fluid using state-of-the-art microscopy and spectroscopy techniques, and evaluates how plastic accumulation in the central nervous...
- The National Institute of Environmental Health Sciences awarded Arizona State University $430,625 on May 15, 2026, under the Environmental Health program (CFDA 93.113) to conduct a multimethod study of micro- and nanoplastics in human brain tissue and their association with Alzheimer's disease and environmental disadvantage. The research quantifies micro- and nanoplastics in the olfactory bulb and middle temporal gyrus of 140 postmortem human brains (70 with Alzheimer's disease pathology, 70...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $152,500 on August 15, 2026, under the Environmental Health program (CFDA 93.113) to define dose-response relationships and renal functional impairment from simultaneous exposure to micro- and nano-plastics and arsenic. The research establishes a quantitative framework for how micro- and nano-plastics behave when co-present with arsenic in the body, whether their excretion is...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $167,928 under the Environmental Health Project Grant program (CFDA 93.113) on April 1, 2026. The project investigates lipoprotein-mediated nanoplastic uptake and transport across the placenta. The research addresses how micro and nanoplastics translocate into placental tissue and the role chylomicrons may play in facilitating this process. The working hypothesis posits that...
- The federal Project Grant award titled "Mechanisms of Nano Plastic Transport in the Brain" was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health Federal Grant Program (CFDA 93.113). The $404,989 grant, awarded on January 15, 2025, will fund research at The Pennsylvania State University (Penn State) to investigate how nanoplastics (plastic particles smaller than one micron) may be transported into the brain via the olfactory...
- The National Institute of Environmental Health Sciences awarded $765,348 to the University of California, Davis on April 14, 2026, under the Environmental Health program (CFDA 93.113) to investigate pollutant-adsorbed nanoplastics and their health impacts following inhalation exposure. The research addresses the formation, distribution, and neurotoxic effects of composite particles created when airborne pollutants adsorb onto nanoplastics. The study employs advanced label-free imaging...
- The National Institute of Environmental Health Sciences awarded the Board of Regents of the University of Nebraska $1,479,178 on September 9, 2025, under the Environmental Health program (CFDA 93.113) to quantify the release of nano- and microplastics from plastic food containers into water and beverages and assess potential health risks. The project measures the release of nano- and microplastics from reusable plastic cups, single-use water and soft drink bottles, and takeaway coffee cups...
- The National Institute of Environmental Health Sciences awarded New York University $10.907 million on September 15, 2025, under the Environmental Health program (CFDA 93.113) to conduct a translational study on the accumulation of micro- and nanoplastic particles in mammalian tissues. The research investigates inter-tissue accumulation of micro- and nanoplastic particles across the lifespan, including the quantified concentration of these particles within systemic tissues, the role of sex, age,...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $390,724 Project Grant to the University of New Mexico to develop a "Standing Wave Acoustics for Nanoplastics Separations (SWANS)" platform. This 2-year project aims to create a proof-of-concept prototype that uses acoustic standing waves to rapidly enrich and isolate plastic nanoparticles from various samples, including bottled water,...
- The National Institute of Environmental Health Sciences awarded $760,000 to the University of California, San Diego on August 26, 2026, under the Environmental Health program (CFDA 93.113) for a Project Grant to develop a placenta-brain axis-on-a-chip platform for studying prenatal neurotoxicity. The recipient will construct a physiologically integrated human co-culture system coupling placental trophoblasts, maternal immune cells, fetal endothelial cells, and cortical organoids via...
The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $419,375 under the Environmental Health program (CFDA 93.113) on August 10, 2026, to explore nanoplastics' neurological effects through investigation of lipid mechanisms and glial inflammation. The recipient will conduct research on micro- and nanoplastics bioaccumulation in the human brain and their molecular interactions within cerebrospinal fluid and the central nervous system. Early laboratory findings indicate that nanoplastics accumulate in brain tissue at higher concentrations than in liver and kidneys, with levels rising over time, and are present as solid particles in cerebrospinal fluid samples. The project will assess how nanoplastic-lipid particle mixtures interact in simulated human cerebrospinal fluid, with particular focus on dysregulation of cholesterol homeostasis and resulting glial inflammation including foam cell formation. Aim 1 will characterize molecular interactions of lipid-nanoplastic mixtures in simulated cerebrospinal fluid using state-of-the-art analytical methods. The award carries a period of performance from August 10, 2026, through August 9, 2028, with place of performance in Albuquerque, New Mexico. The assistance type is a Project Grant, which supports investigator-initiated research under NIEHS's mission to study how environmental exposures affect biological systems across the lifespan and translate findings to reduce disease and promote health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $419.4k | 8/7/26 |