Project Grant R21ES038702
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Cincinnati's Sponsored Research Services Division a $3.87 million Project Grant (CFDA 93.113 – Environmental Health program) on June 10, 2026, with performance extending through June 9, 2030. This research award funds mechanistic and epidemiological investigation into the hepatotoxicity of per- and polyfluoroalkyl substances (PFAS), both legacy compounds (perfluorooctane...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $163,856 Environmental Health Program (CFDA 93.113) Project Grant to the University of New England on April 10, 2026, with a completion date of March 31, 2029. This award funds a prospective research study examining per- and polyfluoroalkyl substances (PFAS) mixtures and their associations with adverse pregnancy outcomes, including spontaneous abortion, preterm birth, and small for...
- Federal Project Grant Award Summary Brown University received a $1.27 million Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded August 6, 2025, with completion targeted for May 31, 2029. The award funds research investigating the relationship between prenatal per- and polyfluoroalkyl substances (PFAS) exposure and adult cardiometabolic disease risk. The research will leverage the New England Family...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded Biota Inc. a $306,585 Phase I Project Grant under the Environmental Health program (CFDA 93.113) effective July 1, 2026, to develop an automated nanoparticle-based workflow for per- and polyfluoroalkyl substances (PFAS) sample preparation and analysis. The primary deliverable is a fully automated platform that eliminates bottlenecks inherent in current solid-phase extraction (SPE) methods by...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded The Pennsylvania State University a $249,000 Project Grant on August 12, 2025, under the Environmental Health program (CFDA 93.113) to conduct research examining the interaction between perinatal organophosphate flame retardant (OPFR) exposure and adult chronic stress on cognitive processing. The project, extending through July 31, 2028, will investigate how early developmental exposure to...
- Federal Project Grant Award Summary Brown University received a $463,850 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded on September 10, 2025, with a completion date of September 9, 2027. The award supports research investigating associations between prenatal per- and polyfluoroalkyl substances (PFAS) mixture exposure and long-term health outcomes in adulthood. The research leverages the New England...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Massachusetts Lowell $157,437 under the Environmental Health program (CFDA 93.113) on May 10, 2025, for a two-year project concluding May 9, 2027. This Project Grant supports research defining the urinary, biliary, and fecal excretion pathways of diverse per- and polyfluoroalkyl substances (PFAS) and investigating the impact of dietary fiber on PFAS elimination. The research...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Southern California a Project Grant of $1.256 million on April 10, 2026, under the Environmental Health program (CFDA 93.113). The award funds a translational research program addressing the health impacts of per- and polyfluoroalkyl substances (PFAS)—commonly known as "forever chemicals"—with a focus on metabolic diseases including obesity, type 2 diabetes, and...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) Environmental Health program (CFDA 93.113) awarded $249,000 to the University of North Carolina at Chapel Hill on August 13, 2025, for a research project extending through July 31, 2028. This Project Grant supports longitudinal research characterizing the early life chemical exposome and its impact on structural and functional brain development in children from birth through age five. The research...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Pennsylvania a $124,728 Project Grant on September 8, 2025, under the Environmental Health program (CFDA 93.113) to conduct research on gestational and childhood exposure to endocrine-disrupting chemicals (EDCs) and their effects on adolescent neurobehavior. The research will deliver scientific investigation into the mechanisms by which EDCs—including polybrominated...
The National Institute of Environmental Health Sciences (NIEHS) awarded The University of Iowa a $427,625 Project Grant on July 7, 2026, under the Environmental Health program (CFDA 93.113) to investigate the neurotoxic effects of per- and polyfluoroalkyl substances (PFAS) on memory and cognitive function. The research will employ a multi-omics approach to identify how human-relevant PFAS mixtures alter gene expression in brain regions associated with memory, specifically the hippocampus and related structures. Using animal models exposed to complex PFAS mixtures, the study aims to characterize individual PFAS compounds responsible for memory impairment and altered gene expression patterns, with the ultimate goal of characterizing environmental contributions to Alzheimer's disease and related dementias (ADRD) and developing preventive strategies. The project, conducted at The University of Iowa in Iowa City, Iowa, will be completed by July 6, 2028. This research addresses a critical knowledge gap regarding how PFAS mixtures—environmental exposures that are modifiable, unlike genetic risk factors—contribute to cognitive decline in older adults. By combining exposomics and transcriptomics data, the study will generate mechanistic insights into environmental health threats and support the NIEHS mission to research how environmental exposures affect biological systems across the lifespan and translate this knowledge to reduce disease and promote population health.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $427.6k | 7/8/26 |