Project Grant R00ES033256
- The Project Grant award titled "CELL-FREE DNA METHYLATION PATTERNS AND MITOCHONDRIAL THERAPEUTICS IN A RODENT MODEL OF ORGANOPHOSPHATE POISONING" is funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The $821,373 award, which runs from August 1, 2025 to May 31, 2030, aims to further delineate the mitochondrial involvement in acute and chronic organophosphate (OP) poisoning. The research project...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $124,728 to The Trustees of the University of Pennsylvania to conduct research on the impact of gestational and childhood exposure to endocrine-disrupting chemicals (EDCs) on adolescent neurobehavior. The key objectives of the research project are to: 1) assess the associations between gestational EDC exposure and...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $546,350 to fund a study to "Define the Neurotoxic and Neurodevelopmental Health Risks of Per- and Polyfluoroalkyl Substances (PFAS)". The key objectives of this 4.5-year research project are to: 1) Characterize the mechanisms by which PFAS facilitate neuronal uptake and accumulation; 2) Elucidate the...
- This Project Grant award, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program, aims to investigate the impact of exposure to organophosphate flame retardants (OPFRs) on metabolic and brain aging. The total funding amount is $409,508, with the award period running from September 16, 2024 to August 31, 2026. The key products and services to be delivered under this grant include: Defining the extent to...
- The federal Project Grant award titled "Mechanisms of Nano Plastic Transport in the Brain" was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health Federal Grant Program (CFDA 93.113). The $404,989 grant, awarded on January 15, 2025, will fund research at The Pennsylvania State University (Penn State) to investigate how nanoplastics (plastic particles smaller than one micron) may be transported into the brain via the olfactory...
- This Project Grant award of $699,956 from the National Institute of Environmental Health Sciences (NIEHS), part of the Environmental Health federal grant program (CFDA 93.113), will support research investigating the genetic and environmental factors that influence the association between prenatal exposure to organophosphate ester flame retardants and plasticizers (OPEs) and the development of autism and attention-deficit/hyperactivity disorder (ADHD) in children. The research will be...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), awarded a $108,514 project grant to The Pennsylvania State University (Penn State) to characterize the pathway by which nanoplastics can be transported from the nose into the central nervous system (CNS). The key research objectives are to investigate the cells involved in this "nose-to-brain" pathway and determine how factors such as sex, age,...
- The federal Project Grant award for "MOLECULAR AND NEURODEVELOPMENTAL ALTERATIONS ASSOCIATED WITH PRENATAL WILDFIRE EXPOSURES" is funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The $795,848 award supports research at the University of California, Davis to investigate the potential impacts of prenatal wildfire smoke exposure on immune regulation, fetal brain development, and child...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a Project Grant of $157,500.00 to the Regents of the University of California at Riverside (UC Riverside) to pilot a study on developmental exposure to per- and polyfluoroalkyl substances (PFAS) and its potential interactions with genetic factors that may contribute to the risk of autism spectrum disorder (ASD). The study aims to investigate how...
- This $409,687 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will support a study to assess the impact of wildfire smoke and heat on cognition, mood, and the human metabolome in a vulnerable older population, specifically those with Parkinson's disease (PD). The research will leverage a large existing case-control study of PD patients and community controls in California's Central...
The federal Project Grant award titled "The Interaction of Perinatal Organophosphate Flame Retardant Exposure and Adult Chronic Stress on Cognitive Processing" is provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health Federal Grant Program (CFDA 93.113). The $249,000 award to The Pennsylvania State University ("Penn State") will support research investigating the combined impacts of early-life exposure to organophosphate flame retardants and chronic adult stress on cognitive function and mental health outcomes. The project aims to elucidate the mechanisms by which these environmental and physiological factors may exacerbate cognitive impairment associated with mental disorders. The award spans the period from August 12, 2025 to July 31, 2028 and leverages Penn State's expertise in areas such as materials science, toxicology, and neuroscience to advance understanding of the complex interplay between chemical exposures and stress on brain function and behavior.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.0k | 8/11/25 |