This federal Project Grant award, with ID R21ES036190, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program. The goal of this $431,750 research project, running from January 2025 to January 2027, is to identify a new innate immune signaling mechanism that is triggered specifically after DNA damage has blocked transcription. The research aims to explain the mechanism by which environmental agents suppressing transcription trigger an innate immune response to alert neighboring cells, as well as determine the physiological impact of such transcription-suppressing environmental agents. The findings from this study are expected to provide a foundation for future research on the link between environmental factors, chronic inflammation, and the efficacy of NF-kB inhibitors as potential therapy.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $431.8k | 1/8/25 |