The National Institutes of Health (NIH) awarded a $390,366 Project Grant (CFDA 93.113 Environmental Health) to The Broad Institute, Inc. to develop high-throughput functional assays and an analytical framework for single-cell resolution measurements of all major DNA repair pathways. The goal is to generate a comprehensive multi-pathway DNA repair dataset integrated with sequencing, proteomics, and other biological data on 500 cell lines. This will enable researchers to better understand the mechanisms underlying genome instability and its relationship to disease. The work will leverage the Broad Institute's expertise in genomics, bioinformatics, and technology development to advance the scientific community's understanding of DNA repair and its role in human health.
Generated 1/28/25, 9:19 AM