Project Grant R01EB039472
- This $1,336,000 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the CFDA 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health" program supports the development of a rapid, motion-robust, and low-gadolinium MRI technology for pediatric brain tumors. The key objectives are to (1) develop cutting-edge technologies for rapid, motion-robust, and quantitative MRI scans to reduce sedation needs...
- The National Institute of Biomedical Imaging and Bioengineering awarded New York University School of Medicine $114,562 on June 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and validate a novel diffusion MRI framework for prostate cancer imaging. The recipient will develop a fast, high-resolution, distortion-free diffusion-weighted imaging protocol for the prostate that overcomes limitations in current...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Leland Stanford Junior University $2,719,451 on August 18, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop next-generation nonstop gated cone-beam computed tomography (NGCBCT) for respiratory gating in stereotactic body radiation therapy for early-stage lung cancer. The project addresses imaging delays and radiation dose...
- The National Cancer Institute awarded Sloan-Kettering Institute for Cancer Research $676,849 on July 1, 2026, under the Cancer Treatment Research program (CFDA 93.395) to enhance MIRDSOFT.ORG, an open-source radiation dosimetry platform operated by the MIRD Committee of the Society of Nuclear Medicine and Molecular Imaging. The award funds development of computational human phantoms and dosimetry software to support personalized dose estimation in nuclear medicine and radiology. Deliverables...
- The National Institute of Biomedical Imaging and Bioengineering awarded The General Hospital Corporation (Massachusetts General Hospital) $249,000 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop engineering strategies that reduce the electromagnetic shielding burden of conventional superconducting MRI systems. The recipient will design, optimize, and experimentally validate passive and active...
- The National Institute of Biomedical Imaging and Bioengineering (part of the Department of Health and Human Services National Institutes of Health) awarded $1.314 million to Massachusetts General Hospital on June 2, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop quantitative point-of-care MRI for breast cancer screening. The research addresses the limitations of current breast cancer screening modalities by...
- The National Cancer Institute, a component of the Department of Health and Human Services, awarded $644,423 to Sloan-Kettering Institute for Cancer Research on June 18, 2026, under the Cancer Treatment Research program (CFDA 93.395). The recipient will develop short-wave infrared (SWIR) Cerenkov luminescence imaging (SWIR-CLI) to visualize the distribution of therapeutic radiotracers and improve monitoring of targeted radiotherapy. Current Cerenkov luminescence imaging requires light-tight...
- The National Cancer Institute awarded Sloan-Kettering Institute for Cancer Research $294,080 on September 3, 2026, under the Cancer Research Manpower program (CFDA 93.398) to develop peripartum breast MRI (PPMRI), a non-contrast MRI technique for detecting breast cancer in pregnant and postpartum women. The award funds development of specialized MRI acquisition methods and biophysical modeling to exploit endogenous contrast mechanisms created by physiological changes during pregnancy and...
- The National Institute of Biomedical Imaging and Bioengineering awarded Vanderbilt University Medical Center $499,651 on June 4, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and validate a prospective head motion correction system for brain MRI using wireless NMR probes. The project addresses motion artifact in MRI, particularly in pediatric imaging, by creating a real-time motion tracking and correction...
- The National Institute of Biomedical Imaging and Bioengineering awarded Northwestern University $255,297 on September 15, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop vertical MRI technology for safe imaging of children with cardiac implantable electronic devices. The project addresses a critical clinical gap: infants and children with congenital heart defects who receive epicardial leads—implanted...
The National Institute of Biomedical Imaging and Bioengineering awarded Sloan-Kettering Institute for Cancer Research $636,110 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop motion-tolerant pediatric MRI technology that reduces anesthesia dependence in tumor imaging. The funded research develops deep learning reconstruction techniques combined with radial k-space acquisition to compensate for patient and respiratory motion during MRI examinations of children with neuroblastoma and Wilms tumor. The project advances auto-navigation methods (RANGR) and reconstruction algorithms (MOVIENET) using self-supervised training and generative diffusion AI models tailored to radial k-space data. Specific deliverables include deep learning techniques for motion-resolved reconstruction of T1-weighted stack-of-stars and T2-weighted propeller acquisitions, and generative AI reconstruction that transforms motion-corrupted images to motion-free images. The work aims to enable MRI examinations without anesthesia, reducing long-term cognitive effects and lowering procedural complexity and cost while improving detection of primary tumor extension and metastases. Performance occurs at Sloan-Kettering Institute in New York, New York, with a period of performance extending from September 1, 2026, through May 31, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $636.1k | 8/18/26 |