Project Grant R21EB040156
- The National Institute of Biomedical Imaging and Bioengineering awarded Massachusetts General Hospital (doing business as The General Hospital Corporation's Research Management Division) $199,616 on May 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286, K99 Project Grant). The award funds development of a deep learning method that fuses three data sources—clinical notes, lab results, and images—to improve disease...
- The National Institute of Biomedical Imaging and Bioengineering (part of the Department of Health and Human Services National Institutes of Health) awarded $1.314 million to Massachusetts General Hospital on June 2, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop quantitative point-of-care MRI for breast cancer screening. The research addresses the limitations of current breast cancer screening modalities by...
- The National Institute of Biomedical Imaging and Bioengineering awarded The General Hospital Corporation (Massachusetts General Hospital) $249,000 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop engineering strategies that reduce the electromagnetic shielding burden of conventional superconducting MRI systems. The recipient will design, optimize, and experimentally validate passive and active...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Davis $615,615 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop next-generation whole-body positron emission tomography (PET) scanners with enhanced spatial resolution and timing performance. The research aims to achieve sub-2 millimeter spatial resolution and approximately 8 cubic millimeter...
- The National Institutes of Health National Heart Lung and Blood Institute awarded The General Hospital Corporation (Massachusetts General Hospital) $121,345 under the Cardiovascular Diseases Research program (CFDA 93.837) on August 15, 2026. The award funds development of positron emission tomography (PET) imaging of oxidized collagen as a biomarker for myocardial fibrosis in heart failure with preserved ejection fraction (HFpEF). The project focuses on targeted PET imaging probes that bind...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Regents of the University of California, operating Lawrence Berkeley National Laboratory, $312,165 on June 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop Time-of-Flight Multi-Photon Emission Tomography (TOF-MPET) for direct imaging of therapeutic radionuclides in cancer treatment. The project addresses limitations in current imaging...
- The National Institute of Biomedical Imaging and Bioengineering awarded $161,000 to the University of California, Davis on May 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop an affordable dynamic total-body positron emission tomography (TB PET) imaging system using sparse detector architectures. The research addresses cost barriers to TB PET adoption by reducing scintillator material and readout electronics...
- The National Institute of General Medical Sciences awarded The General Hospital Corporation (Massachusetts General Hospital) $444,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop secreted genetically encoded fluorescent biosensors for in vivo extracellular imaging. The project will create a toolkit of biosensors across four research areas: imaging extracellular matrix structures by conjugating fluorescent proteins to lectins and...
- Federal Project Grant Award Summary Massachusetts General Hospital (MGH) received a $578,070 Project Grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) awarded August 1, 2025, with completion targeted for July 1, 2026. The award funds the acquisition and installation of the OmniTom Elite Photon Counting Mobile Computed Tomography (CT) Scanner from NeuroLogica. This compact, self-shielded research instrument will be...
- This $1,336,000 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the CFDA 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health" program supports the development of a rapid, motion-robust, and low-gadolinium MRI technology for pediatric brain tumors. The key objectives are to (1) develop cutting-edge technologies for rapid, motion-robust, and quantitative MRI scans to reduce sedation needs...
The National Institute of Biomedical Imaging and Bioengineering awarded The General Hospital Corporation (Massachusetts General Hospital) $100,000 on September 1, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to develop a quantum-inspired computational framework for advanced positron emission tomography (PET) imaging. The project addresses clinical gaps in PET's ability to detect small lesions, distinguish subtle treatment effects, and reduce radiation dose. The framework leverages quantum localization principles to automatically distinguish meaningful image signal from noise without manual parameter tuning or data-driven training. The innovation operates on current high-performance classical computers while remaining structured for future hybrid quantum-classical systems. Work spans three integrated aims: developing a quantum-inspired image-processing pipeline for PET denoising and reconstruction validated in synthetic, phantom, and clinical lung cancer datasets; creating a detector-level method for raw event positioning to improve spatial resolution; and implementing scalable algorithms on hybrid systems. Performance runs from September 1, 2026, through June 30, 2029, at Massachusetts General Hospital's Research Management Division in Charlestown, Massachusetts.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $100.0k | 8/17/26 |