Project Grant R21EB040099
- The National Institute of Biomedical Imaging and Bioengineering awarded Virginia Polytechnic Institute & State University $750,993 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop accurate, robust, and practical pulse-echo speed-of-sound imaging methods for clinical ultrasound applications. The project combines physics-based inversion and deep learning approaches to enable two-dimensional,...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of North Dakota $192,065 on August 15, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a dual-immersion bidirectional light sheet microscopy platform for volumetric imaging across intestinal tissue layers. The project addresses limitations in current imaging tools for capturing dynamic cellular processes in intact...
- The National Institute of Biomedical Imaging and Bioengineering awarded the Trustees of Boston University $232,550 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a mid-infrared photothermal fiber probe for label-free imaging and biomolecular composition analysis in endoscopic applications. The project will develop a fiber-based probe that integrates mid-infrared photothermal imaging with...
- The National Institute of Biomedical Imaging and Bioengineering awarded $182,558 to Iowa State University of Science and Technology on May 6, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a bioinspired drug discovery strategy for personalized combination immunoregulatory therapeutics. The research leverages the foreign body response within subcutaneous biomaterial scaffold implants to identify...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Arlington $378,411 on April 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop super-resolution tomographic imaging technology for deep tissue visualization. The project aims to overcome diffraction limits inherent in existing super-resolution imaging modalities—including super-resolution fluorescence...
- The National Institute of Biomedical Imaging and Bioengineering awarded Duke University $1,523,343 on March 10, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop four-dimensional smart epidermal photoacoustic tomography (4D-SEPAT) technology for real-time, longitudinal functional brain imaging in behaving non-human primates. The 4D-SEPAT system integrates soft ultrasound transducer arrays with integrated shape...
- This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $200,000 to Oakland University aims to develop a novel low-cost, wireless 3D ultrasound imaging system for use in low-resource settings. The key goals are to: 1) establish quantitative tools using signal processing and artificial intelligence to extract ultrasound-derived biomarkers for improved breast cancer diagnosis, and 2) develop a robust calibration, registration, and sensor fusion protocol to...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of North Carolina at Chapel Hill $570,612 on April 7, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop advanced volumetric ultrasound systems for functional imaging and multi-targeted closed-loop neuromodulation. The project addresses current limitations in ultrasonic neuromodulation by moving beyond MRI-dependent targeting...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Texas at Dallas $186,674 on August 7, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop fullwave physics-informed recurrent neural networks for ultrasound simulation, quantitative imaging, and adaptive focusing. The project addresses barriers to clinical adoption of quantitative ultrasound by developing a single...
- Federal Grant Award Summary The University of Wisconsin–Madison received a $427,625 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective September 1, 2025, through August 31, 2027. The project develops and refines photoacoustic imaging (PAI) technology to quantitatively assess cutaneous wound healing by measuring biomarkers of...
The National Institute of Biomedical Imaging and Bioengineering awarded Iowa State University of Science and Technology $215,723 on August 14, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a next-generation, handheld, battery-powered, wireless dual-mode ultrasound-photoacoustic imaging system integrating high-power nanosecond pulsed light-emitting diodes. The project addresses a gap in current imaging capabilities for visualizing vascular and lymphatic system function in real time. Existing modalities—including X-ray CT, MRI, ultrasound, and optical techniques—either lack functional sensitivity, lack penetration depth, or remain confined to superficial layers. Current photoacoustic imaging systems depend on bulky, high-energy Class IV laser systems exceeding 100 kilograms and costing over $150,000, requiring optical tables and dedicated facilities, which prevents clinical translation to bedside, operating room, or low-resource settings. The proposed wireless ultrasound-photoacoustic system combines optical absorption contrast with ultrasound resolution in a fully handheld, battery-powered form factor. The award period runs from August 14, 2026, to July 31, 2029, with work performed in Ames, Iowa.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $215.7k | 8/14/26 |