Project Grant R21EB036580
Award Date
7/15/25
Completion Date
6/30/27
Dollars Obligated
$212K
Federal Agency
National Institute of Biomedical Imaging and Bioenginering
Awardee
Duke University (TP7EK8DZV6N5)
Federal Grant Program
93.286
Assistance Type
Project Grant
Place of Performance
North Carolina, USA
Similar Awards
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $185,171 to The Johns Hopkins University to optimize polymeric chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) agents for prostate cancer detection. The research aims to synthesize and characterize CEST MRI agents with varying charge and...
This $381,100 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports the development and evaluation of tumor-targeting polymeric micelles carrying a near-infrared (NIR) imaging agent. The goal is to provide real-time optical image guidance during brain cancer surgery to improve tumor resection and surgical outcomes. The project aims to: 1) develop and characterize the tumor-targeting polymeric...
This Project Grant award from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) provides $997,410 to Arizona State University, in collaboration with Mayo Clinic Arizona, to develop non-invasive magnetic resonance imaging (MRI) techniques for detecting and differentiating between the invasive neuronal (NEU) and glycolytic/plurimetabolic (GPM) subtypes of high-grade glioma brain tumors. The key objectives are to: Establish and validate...
The National Cancer Institute (CFDA 93.396 - Cancer Biology Research) awarded Loyola University of Chicago a $461,844 project grant titled "Hyperpolarized 13C Metabolic Imaging of Tumorigenesis in the Liver". The objective is to use novel hyperpolarized 13C probes to image glycolysis, a critical pathway in hepatocellular carcinoma (HCC) development, and establish in vivo imaging biomarkers to assess altered liver metabolism during HCC progression. The project aims to synthesize a...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the federal Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $174,375.00 to The Johns Hopkins University from December 5, 2024 to November 30, 2027. The project aims to develop new methods for incorporating the radioactive isotope fluorine-18 into complex biomolecules using metal-fluorine bond formation. This will...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $305,000 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to Odmr Technologies, Inc. to develop a miniature diamond quantum sensor for magnetoencephalography (MEG). The key objectives are to: 1) Build a miniature flux-concentrator diamond sensor with infrared absorption detection, and 2) Demonstrate a sensitivity of ~10 femtotesla for 1 second...
This $384,863 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program supports research to develop a novel radiotracer imaging agent for detecting Gram-positive bacterial infections associated with implanted medical devices. The key products and services to be delivered include: In vitro testing of a bivalent radiotracer agent...
The National Cancer Institute (NCI) awarded a $400,000 Project Grant under CFDA 93.394 (Cancer Detection and Diagnosis Research) to O2M Technologies LLC to develop a Multifunctional Imager (MFI) that can simultaneously acquire tissue oxygen pressure (pO2) and pH maps using electron paramagnetic resonance imaging (EPRI) techniques. The 12-month project aims to create a 25 MT Halbach-type permanent magnet, new multi-modal transmit-receive electronics, and the integrated MFI instrument. This...
This $497,196 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports the development of a novel magnetic resonance spectroscopic imaging (MRSI) pulse sequence at 3 Tesla. The goal is to simultaneously map both downfield and upfield proton metabolic signals in the human brain, which may provide important new insights into brain metabolism....
This $390,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) will support the development of a multiparametric fluorescence microscopy framework to correlate metabolic changes with cellular manipulations and physical/biophysical properties. The award, granted to Georgetown University, will establish a seamless workflow to quantify and correlate fundamental cellular interactions, such as...