This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $1,336,000.00 to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop rapid, motion-robust, and low-gadolinium MRI techniques for improved diagnosis and monitoring of pediatric brain tumors. The key objectives are to: (I) Develop cutting-edge technologies for rapid, motion-robust, and quantitative MRI scans that reduce the need for sedation and mitigate long-term cognitive effects on children; and (II) Synthesize clinically desired full-dose post-contrast images from low-dose quantitative MRI data. The project aims to address unmet needs in pediatric brain tumor imaging by advancing MRI methods to enhance image quality, reduce sedation requirements, and minimize gadolinium exposure. The technologies will be rigorously evaluated on non-sedated pediatric patients and compared to standard post-contrast imaging. All developed techniques will be disseminated through Siemens Healthineers' software platforms to facilitate broader clinical adoption.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $0 | 11/5/24 | ||
| Not listed | $668.0k | 8/26/24 | ||
| Not listed | $668.0k | 8/26/24 |