The General Hospital Corporation Research Management Division, doing business as Massachusetts General Hospital (MGH), received a $185,625 Project Grant (R21EB036303) from the National Institute of Biomedical Imaging and Bioengineering (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to develop an innovative magnetic resonance imaging (MRI) technology. The project aims to address the flip angle inhomogeneity problem in high-field 7 Tesla MRI systems, which has hindered their clinical translation, by introducing a multiphoton parallel transmit excitation scheme. This approach utilizes a conventional birdcage RF coil supplemented with low-frequency transmitters to shape the magnetization distribution and achieve highly uniform flip angle distributions in the brain region-of-interest. The project will validate this multiphoton parallel transmit approach for improved 7 Tesla brain imaging in phantom and human studies over the 2-year award period from February 2025 to January 2027.
Generated 3/4/25, 8:12 AM