Project Grant R21NS140619

Award Date 12/1/24
Completion Date 11/30/26
Dollars Obligated $408K
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Charlestown, MA 02129, USA
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The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,458,572 Cooperative Agreement under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to National Technology & Engineering Solutions of Sandia, LLC (Sandia Corp) to develop closed-loop triaxial optically pumped magnetometers for high-sensitivity and high-bandwidth magnetoencephalography (MEG) measurements of the developing brain. The funding will...
This Project Grant awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research to identify optimal electrophysiological markers for predicting developmental outcomes in infants. The $147,037 award to The Children's Hospital of Philadelphia Research Institute will fund a study examining the similarity between resting-state and auditory...
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This Project Grant award of $408,400 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will fund the development and assessment of a wearable magnetoencephalography (MEG) system for use in children. The funding will support two key objectives:

  1. Developing and optimizing an optically pumped magnetometers (OPM)-based MEG recording system that can accommodate the variable head sizes of children and minimize movement artifacts. This will involve designing age-matched helmets and incorporating additional nulling coils and software to suppress artifacts.

  2. Evaluating the new OPM-MEG system on healthy children and pediatric epilepsy patients to compare its performance to traditional SQUID-based MEG systems in localizing interictal epileptiform discharges, which is critical for surgical planning. The project will run from December 1, 2024 to November 30, 2026.

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