Project Grant R21DE034107
Award Date
7/1/25
Completion Date
6/30/27
Dollars Obligated
$239K
Federal Agency
National Institute of Dental and Craniofacial Research
Federal Grant Program
93.121
Assistance Type
Project Grant
Place of Performance
Charlestown, MA 02129, USA
Similar Awards
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $3,565,780 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop a groundbreaking high-frequency trans-spinal magnetic stimulation (HF-TSMS) system for the non-invasive treatment of neuropathic pain. The funded project aims to create an HF-TSMS tool that can target neural pathways involved in...
This $14.2 million project grant from the National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, will fund research from September 2022 to August 2025 under the Drug Abuse and Addiction Research Programs (CFDA 93.279). The Massachusetts General Hospital will investigate the mechanisms by which spinal cord stimulation reduces pain, with the goal of improving device design and patient selection. Researchers will apply specialized nerve...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), part of the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), provides $1,831,197 to Emory University to conduct research on nociplastic pain mechanisms in temporomandibular disorders (TMD). The research project aims to separate nociceptive (stimulus-evoked) sensitivity from pain sensitivity using novel quantitative sensory testing methods, in order to better understand the...
This $5,037,022 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will support the development of novel single-cell technologies called "Raman2omics" to map pain-associated genes and cells across the lifespan. Funded under the Drug Abuse and Addiction Research Programs, the grant to the Massachusetts General Hospital aims to apply Raman2omics to systematically investigate genes and cells associated with postoperative pain...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $6,522,833 Project Grant to The Leland Stanford Junior University to conduct a mechanistic randomized clinical trial investigating the central and peripheral nervous system mechanisms of pain relief induced by peripheral nerve stimulation (PNS) for the treatment of refractory chronic neuropathic pain. The 3-year study, funded under the NIH HEAL Initiative's CFDA 93.279 Drug Abuse and Addiction Research Programs, aims...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $162,743 to New York University (NYU) to conduct research on the role of Schwann cells and the TRPV4 ion channel in oral cancer pain mechanisms. The 5-year award, which commenced on March 10, 2025, aims to develop and validate new methods for measuring pressure and stretch sensitivity associated with oral cancer...
This federal Project Grant award in the amount of $351,097 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), which is part of the National Institutes of Health (NIH). The grant was awarded under the NIH's Drug Use and Addiction Research Programs (CFDA 93.279) to establish a rigorous and supportive interdisciplinary training program in clinical pain research at Mass General Brigham (MGB) in Boston. The program will support a diverse pool of 8 postdoctoral...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is providing $124,713 to Beth Israel Deaconess Medical Center, Inc. (BIDMC) to identify a circuit basis for neuropathic pain in the parabrachial nucleus. The research aims to understand how different pain-related stimuli are integrated in the parabrachial nucleus, determine if specific...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded an $11.2 million project grant to the University of Pittsburgh to define the mechanisms of pain relief associated with dorsal root ganglion and spinal cord stimulation. This three-year grant will support research under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to advance understanding of neuromodulatory devices for chronic pain treatment. The University will conduct preclinical...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,849,232.90 project grant (CFDA 93.121 - Oral Diseases and Disorders Research) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), with a period of performance from September 1, 2024 to May 31, 2028. The goal of this project is to identify the cellular and molecular identity of genes and pathways defining dental mesenchymal cell differentiation and fate early in tooth...