This $5,037,022 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will support the development of novel single-cell technologies called "Raman2omics" to map pain-associated genes and cells across the lifespan. Funded under the Drug Abuse and Addiction Research Programs, the grant to the Massachusetts General Hospital aims to apply Raman2omics to systematically investigate genes and cells associated with postoperative pain in a mouse model. This will generate molecular information to identify biomarkers and therapeutic targets for chronic pain. Additionally, the single-cell technologies developed have broad applicability to study other multcellular tissues in health and disease. The work commenced on September 15, 2022 and is scheduled to conclude on August 31, 2025.
Generated 1/6/24, 3:27 PM