Not listed CHARACTERIZING LANGUAGE AND MOTOR DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS AND TODDLERS WITH DOWN SYNDROME - PROJECT SUMMARY/ABSTRACT DOWN SYNDROME (DS) IMPACTS APPROXIMATELY 1 IN ABOUT 700 BABIES BORN IN THE UNITED STATES. LANGUAGE AND MOTOR DEVELOPMENT IN DS ARE SIGNIFICANTLY DELAYED IN EARLY CHILDHOOD; HOWEVER, LITTLE RESEARCH HAS INVESTIGATED HOW LANGUAGE AND MOTOR SKILLS INTERACT AND SUPPORT EACH OTHER. IN RESPONSE TO THE NIH INCLUDE DOWN SYNDROME RESEARCH PLAN, THE PROPOSED STUDY WILL ADDRESS SEVERAL GAPS IN OUR UNDERSTANDING OF DS. FIRST, WE WILL IMPLEMENT MULTIPLE METHODS, INCLUDING TECHNOLOGY, TO MEASURE LANGUAGE AND MOTOR DEVELOPMENT ACROSS DIRECT ASSESSMENTS, NATURALISTIC MEASUREMENTS, PARENT REPORTS, AND FREE PLAY OBSERVATIONS. SECOND, WE INTEND TO ACTIVELY RECRUIT AND ENROLL OVER 60% OF PARTICIPANTS FROM RACIALLY/ETHNICALLY MINORITIZED BACKGROUNDS. FINALLY, WE WILL COLLECT LONGITUDINAL DATA TO TRACK MEASURES THAT MAY BE SENSITIVE TO DEVELOPMENTAL CHANGE. USING MULTIPLE METHODS, WE WILL TRACK DEVELOPMENTAL TRAJECTORIES OF LANGUAGE AND MOTOR SKILLS IN INFANTS WITH DOWN SYNDROME (DS) AND TYPICALLY DEVELOPING INFANTS OVER A 12-MONTH PERIOD. THE GOAL IS TO MEASURE LANGUAGE, COMMUNICATION, MOTOR SKILLS, AND PHYSICAL ACTIVITY TO BETTER UNDERSTAND HOW THESE SKILLS DEVELOP AND INTERACT WITH EACH OTHER OVER TIME. IF FUNDED, WE WILL RECRUIT 36 INFANTS WITH DS (AGE 6 MONTHS - 18 MONTHS) AND 36 TYPICALLY DEVELOPING (TD) INFANTS (AGE 6 MONTHS - 18 MONTHS) AND FOLLOW THEM FOR 12 MONTHS. WE INTEND TO RECRUIT AT LEAST 60% OF OUR SAMPLE FROM RACIAL/ETHNIC MINORITY BACKGROUNDS (I.E., HISPANIC/LATINO, BLACK/AFRICAN AMERICAN, ASIAN, NATIVE AMERICAN). INFANTS AND THEIR CAREGIVERS WILL COMPLETE STANDARDIZED QUESTIONNAIRES AND ASSESSMENTS AT STUDY ENTRY, THEN TWO MORE TIMES, 6 MONTHS APART, FOR A TOTAL OF THREE ASSESSMENTS IN A 12- MONTH PERIOD OF TIME. THIS RESEARCH WILL PROVIDE CRITICAL DATA ON THE EARLY DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS WITH DS TO INFORM INTERVENTION STRATEGIES AND SUPPORTS. $0 3/2/26 Not listed CHARACTERIZING LANGUAGE AND MOTOR DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS AND TODDLERS WITH DOWN SYNDROME - PROJECT SUMMARY/ABSTRACT DOWN SYNDROME (DS) IMPACTS APPROXIMATELY 1 IN ABOUT 700 BABIES BORN IN THE UNITED STATES. LANGUAGE AND MOTOR DEVELOPMENT IN DS ARE SIGNIFICANTLY DELAYED IN EARLY CHILDHOOD; HOWEVER, LITTLE RESEARCH HAS INVESTIGATED HOW LANGUAGE AND MOTOR SKILLS INTERACT AND SUPPORT EACH OTHER. IN RESPONSE TO THE NIH INCLUDE DOWN SYNDROME RESEARCH PLAN, THE PROPOSED STUDY WILL ADDRESS SEVERAL GAPS IN OUR UNDERSTANDING OF DS. FIRST, WE WILL IMPLEMENT MULTIPLE METHODS, INCLUDING TECHNOLOGY, TO MEASURE LANGUAGE AND MOTOR DEVELOPMENT ACROSS DIRECT ASSESSMENTS, NATURALISTIC MEASUREMENTS, PARENT REPORTS, AND FREE PLAY OBSERVATIONS. SECOND, WE INTEND TO ACTIVELY RECRUIT AND ENROLL OVER 60% OF PARTICIPANTS FROM RACIALLY/ETHNICALLY MINORITIZED BACKGROUNDS. FINALLY, WE WILL COLLECT LONGITUDINAL DATA TO TRACK MEASURES THAT MAY BE SENSITIVE TO DEVELOPMENTAL CHANGE. USING MULTIPLE METHODS, WE WILL TRACK DEVELOPMENTAL TRAJECTORIES OF LANGUAGE AND MOTOR SKILLS IN INFANTS WITH DOWN SYNDROME (DS) AND TYPICALLY DEVELOPING INFANTS OVER A 12-MONTH PERIOD. THE GOAL IS TO MEASURE LANGUAGE, COMMUNICATION, MOTOR SKILLS, AND PHYSICAL ACTIVITY TO BETTER UNDERSTAND HOW THESE SKILLS DEVELOP AND INTERACT WITH EACH OTHER OVER TIME. IF FUNDED, WE WILL RECRUIT 36 INFANTS WITH DS (AGE 6 MONTHS - 18 MONTHS) AND 36 TYPICALLY DEVELOPING (TD) INFANTS (AGE 6 MONTHS - 18 MONTHS) AND FOLLOW THEM FOR 12 MONTHS. WE INTEND TO RECRUIT AT LEAST 60% OF OUR SAMPLE FROM RACIAL/ETHNIC MINORITY BACKGROUNDS (I.E., HISPANIC/LATINO, BLACK/AFRICAN AMERICAN, ASIAN, NATIVE AMERICAN). INFANTS AND THEIR CAREGIVERS WILL COMPLETE STANDARDIZED QUESTIONNAIRES AND ASSESSMENTS AT STUDY ENTRY, THEN TWO MORE TIMES, 6 MONTHS APART, FOR A TOTAL OF THREE ASSESSMENTS IN A 12- MONTH PERIOD OF TIME. THIS RESEARCH WILL PROVIDE CRITICAL DATA ON THE EARLY DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS WITH DS TO INFORM INTERVENTION STRATEGIES AND SUPPORTS. $0 3/2/26 Not listed CHARACTERIZING LANGUAGE AND MOTOR DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS AND TODDLERS WITH DOWN SYNDROME - PROJECT SUMMARY/ABSTRACT DOWN SYNDROME (DS) IMPACTS APPROXIMATELY 1 IN ABOUT 700 BABIES BORN IN THE UNITED STATES. LANGUAGE AND MOTOR DEVELOPMENT IN DS ARE SIGNIFICANTLY DELAYED IN EARLY CHILDHOOD; HOWEVER, LITTLE RESEARCH HAS INVESTIGATED HOW LANGUAGE AND MOTOR SKILLS INTERACT AND SUPPORT EACH OTHER. IN RESPONSE TO THE NIH INCLUDE DOWN SYNDROME RESEARCH PLAN, THE PROPOSED STUDY WILL ADDRESS SEVERAL GAPS IN OUR UNDERSTANDING OF DS. FIRST, WE WILL IMPLEMENT MULTIPLE METHODS, INCLUDING TECHNOLOGY, TO MEASURE LANGUAGE AND MOTOR DEVELOPMENT ACROSS DIRECT ASSESSMENTS, NATURALISTIC MEASUREMENTS, PARENT REPORTS, AND FREE PLAY OBSERVATIONS. SECOND, WE INTEND TO ACTIVELY RECRUIT AND ENROLL OVER 60% OF PARTICIPANTS FROM RACIALLY/ETHNICALLY MINORITIZED BACKGROUNDS. FINALLY, WE WILL COLLECT LONGITUDINAL DATA TO TRACK MEASURES THAT MAY BE SENSITIVE TO DEVELOPMENTAL CHANGE. USING MULTIPLE METHODS, WE WILL TRACK DEVELOPMENTAL TRAJECTORIES OF LANGUAGE AND MOTOR SKILLS IN INFANTS WITH DOWN SYNDROME (DS) AND TYPICALLY DEVELOPING INFANTS OVER A 12-MONTH PERIOD. THE GOAL IS TO MEASURE LANGUAGE, COMMUNICATION, MOTOR SKILLS, AND PHYSICAL ACTIVITY TO BETTER UNDERSTAND HOW THESE SKILLS DEVELOP AND INTERACT WITH EACH OTHER OVER TIME. IF FUNDED, WE WILL RECRUIT 36 INFANTS WITH DS (AGE 6 MONTHS - 18 MONTHS) AND 36 TYPICALLY DEVELOPING (TD) INFANTS (AGE 6 MONTHS - 18 MONTHS) AND FOLLOW THEM FOR 12 MONTHS. WE INTEND TO RECRUIT AT LEAST 60% OF OUR SAMPLE FROM RACIAL/ETHNIC MINORITY BACKGROUNDS (I.E., HISPANIC/LATINO, BLACK/AFRICAN AMERICAN, ASIAN, NATIVE AMERICAN). INFANTS AND THEIR CAREGIVERS WILL COMPLETE STANDARDIZED QUESTIONNAIRES AND ASSESSMENTS AT STUDY ENTRY, THEN TWO MORE TIMES, 6 MONTHS APART, FOR A TOTAL OF THREE ASSESSMENTS IN A 12- MONTH PERIOD OF TIME. THIS RESEARCH WILL PROVIDE CRITICAL DATA ON THE EARLY DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS WITH DS TO INFORM INTERVENTION STRATEGIES AND SUPPORTS. $779 5/1/25 Not listed CHARACTERIZING LANGUAGE AND MOTOR DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS AND TODDLERS WITH DOWN SYNDROME - PROJECT SUMMARY/ABSTRACT DOWN SYNDROME (DS) IMPACTS APPROXIMATELY 1 IN ABOUT 700 BABIES BORN IN THE UNITED STATES. LANGUAGE AND MOTOR DEVELOPMENT IN DS ARE SIGNIFICANTLY DELAYED IN EARLY CHILDHOOD; HOWEVER, LITTLE RESEARCH HAS INVESTIGATED HOW LANGUAGE AND MOTOR SKILLS INTERACT AND SUPPORT EACH OTHER. IN RESPONSE TO THE NIH INCLUDE DOWN SYNDROME RESEARCH PLAN, THE PROPOSED STUDY WILL ADDRESS SEVERAL GAPS IN OUR UNDERSTANDING OF DS. FIRST, WE WILL IMPLEMENT MULTIPLE METHODS, INCLUDING TECHNOLOGY, TO MEASURE LANGUAGE AND MOTOR DEVELOPMENT ACROSS DIRECT ASSESSMENTS, NATURALISTIC MEASUREMENTS, PARENT REPORTS, AND FREE PLAY OBSERVATIONS. SECOND, WE INTEND TO ACTIVELY RECRUIT AND ENROLL OVER 60% OF PARTICIPANTS FROM RACIALLY/ETHNICALLY MINORITIZED BACKGROUNDS. FINALLY, WE WILL COLLECT LONGITUDINAL DATA TO TRACK MEASURES THAT MAY BE SENSITIVE TO DEVELOPMENTAL CHANGE. USING MULTIPLE METHODS, WE WILL TRACK DEVELOPMENTAL TRAJECTORIES OF LANGUAGE AND MOTOR SKILLS IN INFANTS WITH DOWN SYNDROME (DS) AND TYPICALLY DEVELOPING INFANTS OVER A 12-MONTH PERIOD. THE GOAL IS TO MEASURE LANGUAGE, COMMUNICATION, MOTOR SKILLS, AND PHYSICAL ACTIVITY TO BETTER UNDERSTAND HOW THESE SKILLS DEVELOP AND INTERACT WITH EACH OTHER OVER TIME. IF FUNDED, WE WILL RECRUIT 36 INFANTS WITH DS (AGE 6 MONTHS - 18 MONTHS) AND 36 TYPICALLY DEVELOPING (TD) INFANTS (AGE 6 MONTHS - 18 MONTHS) AND FOLLOW THEM FOR 12 MONTHS. WE INTEND TO RECRUIT AT LEAST 60% OF OUR SAMPLE FROM RACIAL/ETHNIC MINORITY BACKGROUNDS (I.E., HISPANIC/LATINO, BLACK/AFRICAN AMERICAN, ASIAN, NATIVE AMERICAN). INFANTS AND THEIR CAREGIVERS WILL COMPLETE STANDARDIZED QUESTIONNAIRES AND ASSESSMENTS AT STUDY ENTRY, THEN TWO MORE TIMES, 6 MONTHS APART, FOR A TOTAL OF THREE ASSESSMENTS IN A 12- MONTH PERIOD OF TIME. THIS RESEARCH WILL PROVIDE CRITICAL DATA ON THE EARLY DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS WITH DS TO INFORM INTERVENTION STRATEGIES AND SUPPORTS. ($39k) 4/21/25 Not listed CHARACTERIZING LANGUAGE AND MOTOR DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS AND TODDLERS WITH DOWN SYNDROME - ABSTRACT WE ARE REQUESTING A RESEARCH SUPPLEMENT TO PROMOTE DIVERSITY IN HEALTH-RELATED RESEARCH (PA-23-189) TO SUPPORT ASHLEY REYES-MONROY TO WORK ON THE PARENT GRANT "CHARACTERIZING LANGUAGE AND MOTOR DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS AND TODDLERS WITH DOWN SYNDROME" (R21DC021818). DOWN SYNDROME (DS) IMPACTS APPROXIMATELY 1 IN ABOUT 700 BABIES BORN IN THE UNITED STATES. LANGUAGE AND MOTOR DEVELOPMENT IN DS ARE SIGNIFICANTLY DELAYED IN EARLY CHILDHOOD; HOWEVER, LITTLE RESEARCH HAS INVESTIGATED HOW LANGUAGE AND MOTOR SKILLS INTERACT AND SUPPORT EACH OTHER. IN RESPONSE TO THE NIH INCLUDE DOWN SYNDROME RESEARCH PLAN, THE FUNDED STUDY WILL ADDRESS SEVERAL GAPS IN OUR UNDERSTANDING OF DS. USING MULTIPLE METHODS, WE WILL TRACK DEVELOPMENTAL TRAJECTORIES OF LANGUAGE AND MOTOR SKILLS IN INFANTS WITH DS AND TYPICALLY DEVELOPING INFANTS OVER A 12-MONTH PERIOD. THE GOAL IS TO MEASURE LANGUAGE, COMMUNICATION, MOTOR SKILLS, AND PHYSICAL ACTIVITY TO BETTER UNDERSTAND HOW THESE SKILLS DEVELOP AND INTERACT WITH EACH OTHER OVER TIME. WE WILL RECRUIT 36 INFANTS WITH DS (AGE 6 MONTHS - 18 MONTHS) AND 36 TYPICALLY DEVELOPING (TD) INFANTS (AGE 6 MONTHS - 18 MONTHS) AND FOLLOW THEM FOR 12 MONTHS. WE INTEND TO RECRUIT AT LEAST 60% OF OUR SAMPLE FROM RACIAL/ETHNIC MINORITY BACKGROUNDS (I.E., HISPANIC/LATINO, BLACK/AFRICAN AMERICAN, ASIAN, NATIVE AMERICAN). INFANTS AND THEIR CAREGIVERS WILL COMPLETE STANDARDIZED QUESTIONNAIRES AND ASSESSMENTS AT STUDY ENTRY, THEN TWO MORE TIMES, 6 MONTHS APART, FOR A TOTAL OF THREE ASSESSMENTS IN A 12-MONTH PERIOD. THIS RESEARCH WILL PROVIDE CRITICAL DATA ON THE EARLY DEVELOPMENT OF RACIALLY/ETHNICALLY DIVERSE INFANTS WITH DS TO INFORM INTERVENTION STRATEGIES AND SUPPORTS. MS. REYES-MONROY RECENTLY COMPLETED HER BACHELOR'S DEGREE IN NEUROSCIENCE IN MAY 2024 AND HAS A DEMONSTRATED INTEREST IN AND DESIRE TO PURSUE RESEARCH TRAINING IN HEALTH-RELATED SCIENCES WITH A GOAL OF PURSUING HER MD AND PHD. SHE IS SPECIFICALLY INTERESTED IN GAINING ADDITIONAL CLINICAL PRACTICE RESEARCH EXPERIENCE WITH CHILDREN WITH NEURODEVELOPMENTAL DISABILITIES. WE ARE REQUESTING FUNDING FOR HER SALARY FOR 12 MONTHS ACROSS 1 PARENT GRANT BUDGET PERIOD. AS A HISPANIC FEMALE, THE APPOINTMENT OF MS. REYES-MONROY WILL HELP ADDRESS THE ISSUE OF DIVERSITY WITHIN THE NATIONAL SCIENTIFIC WORKFORCE. HISPANIC WOMEN COMPRISE ONLY 6.4% OF THE WORKFORCE IN SCIENCE AND ENGINEERING.1 AS SUCH, ADDITIONAL RESEARCH DEVELOPMENT OPPORTUNITIES ARE ESSENTIAL FOR HISPANIC WOMEN TO ADDRESS THIS DISPARITY. ($39k) 4/21/25