Project Grant R21DA063816
- Federal Grant Award Summary Washington State University received a $639,915 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded February 15, 2026, with completion targeted for December 31, 2030. The award supports research investigating the mechanistic underpinnings of cognitive inflexibility in offspring exposed to cannabis prenatally. The research employs a novel, translationally relevant animal model...
- Federal Grant Award Summary Washington State University received a $153,000 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning June 15, 2025, and concluding May 31, 2027. The award supports a six-month longitudinal research study examining the relationship between naturalistic cannabis use and daily functioning in young adults with chronic pain using an innovative ecological momentary assessment burst...
- Federal Grant Award Summary George Washington University received a $159,139 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded August 15, 2025, with completion targeted for July 31, 2030. The project investigates the impact of derived psychoactive cannabis products (DPCPs) marketing on perceptions and use among young adults. This research addresses the gap created by the 2018 U.S. Farm Bill, which legalized...
- Federal Grant Award Summary The University of Washington received a $699,748 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded February 15, 2026, with completion targeted for November 30, 2030. The grant funds a longitudinal neurodevelopmental research study investigating the effects of prenatal cannabis exposure on infant brain development and growth trajectories during the critical first 18 months of life....
- Federal Project Grant Award Summary Oregon Health & Science University received a $429,000 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) awarded July 15, 2025, with a completion date of June 30, 2027. The award funds research to develop innovative photopharmacological tools for investigating tetrahydrocannabinol (THC) signaling mechanisms in brain reward circuits. The primary deliverable is the advancement...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Johns Hopkins University a $194,271 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) effective May 1, 2026 through April 30, 2028. This R21 Exploratory/Developmental Research project aims to optimize rodent models for drug discrimination and self-administration studies using vaporized cannabis extracts to advance medications development for Cannabis Use Disorder (CUD). The research...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Lawrence Berkeley National Laboratory $493,444 under the Drug Use and Addiction Research Programs (CFDA 93.279) Project Grant, effective March 15, 2026, with completion targeted for December 31, 2028. The grant supports fundamental research investigating the control principles underlying neural population dynamics, with specific application to understanding how feedback mechanisms shape brain function relevant to...
- Federal Grant Award Summary The University of Washington received a $139,812 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), effective August 6, 2026, with a completion date of March 15, 2029. This research initiative investigates the neurobiological mechanisms by which kappa opioid receptor (KOR) activation—triggered by the endogenous neuropeptide dynorphin during stress—modulates serotonin (5HT) and dopamine...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Washington University a Project Grant of $116,865 on August 3, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the role of locus coeruleus mu opioid receptors in fentanyl drug seeking. The research addresses the escalating opioid epidemic by examining how mu opioid receptors (MOR) in the locus coeruleus—the brain region originating the central noradrenergic system—modulate...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Leland Stanford Junior University a $160,840 Project Grant effective August 1, 2026, through July 31, 2028, under the Drug Use and Addiction Research Programs (CFDA 93.279). This K99/R00 award funds a two-year research initiative investigating the differential vascular and neuronal effects of natural cannabinoids (such as cannabidiol and delta-9-tetrahydrocannabinol) versus synthetic cannabinoids (such as...
Award Overview
Washington State University received a $420,750 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded July 15, 2026, with a completion date of June 30, 2028. The award funds research to investigate the neurobiological substrates underlying cannabis-seeking behavior, specifically examining how dynamic neural activity and dopamine release in brain circuits correlate with cannabis use. Research Products and Services
The project delivers preclinical research investigating cannabis-seeking behavior using a translational animal model involving response-contingent delivery of vaporized cannabis extracts to rats. The research employs wireless fiber photometry systems to measure real-time neural activity in specific brain circuits—particularly neurons projecting from the prelimbic medial prefrontal cortex to the nucleus accumbens core—while monitoring local dopamine release dynamics. Findings from this research are intended to elucidate mechanisms underlying cannabis addiction and conditioned drug-seeking behavior in the presence of drug-predictive cues, with potential applications to understanding human cannabis use disorder. The work will generate neurobiological data on how corticostriatal circuit activity supports cannabis-seeking behavior, contributing to the broader NIDA mission of developing prevention and treatment approaches for substance use disorders.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $420.8k | 7/7/26 |