Project Grant R21DA062756
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $2.76 million Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Alabama at Birmingham for research investigating the prefrontal circuits that control heroin-seeking behavior in opioid use disorder (OUD). The award, effective April 1, 2025, through January 31, 2030, supports preclinical research examining two functionally opposing prefrontal subcircuits: the...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $781,032 to The Research Foundation for the State University of New York (RF SUNY) on August 1, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support a five-year research project through April 30, 2030. This Project Grant funds fundamental neuroscience research investigating the interplay between limbic norepinephrine (NE) and dopamine (DA) circuits and their role in sex differences in...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Oklahoma Health Sciences Center a Project Grant totaling $348,756 under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and evaluate a mobile health intervention designed to support postpartum individuals recovering from opioid use disorder (OUD). The research initiative, titled "Postpartum Recovery from Opioid Use Disorder Through Daily Acceptance and Commitment...
- Federal Grant Award Summary The Oklahoma Medical Research Foundation received a $648,389 Project Grant award from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning February 15, 2026, with completion targeted for November 30, 2030. This award supports basic research investigating cell type-specific neurotensin signaling in methamphetamine use disorder, a chronic and progressive condition currently lacking FDA-approved therapeutic...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Oklahoma Health Sciences Center a $1.5 million Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) effective August 1, 2025, with completion targeted for May 31, 2030. This research project investigates the addiction potential, flavoring content, and substitutability of concept-flavored cigarillos—vague, ambiguous flavor descriptors used by tobacco companies to...
- Federal Grant Award Summary The National Institute on Drug Abuse awarded the University of Colorado a Project Grant totaling $127,401 under the Drug Use and Addiction Research Programs (CFDA 93.279) on October 14, 2025, with a completion date of May 15, 2028. This research project investigates the neural mechanisms underlying opioid withdrawal-induced anxiety through a combination of behavioral animal models and advanced neurotechnological techniques. The research integrates two complementary...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of South Carolina a Project Grant of $192,149 under the Drug Use and Addiction Research Programs (CFDA 93.279) for the period February 1, 2026, through January 31, 2028. This research project investigates the noradrenergic mechanisms underlying stress-induced opioid reinstatement, specifically examining how stress exposure triggers increased cytokine release and heightened activity in the locus...
- Federal Project Grant Award Summary New York University School of Medicine received a $1.45 million Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), effective July 1, 2025, through March 31, 2030. This research project will characterize complex opioid use disorder (OUD) care trajectories and outcomes following acute service utilization through a population-based data linkage study. The primary deliverable is...
- Federal Project Grant Award Summary The Medical University of South Carolina received a $415,250 Project Grant award effective July 1, 2025, through June 30, 2027, from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports research investigating the role of cortical astroglia in heroin seeking behaviors, utilizing advanced neuroimaging techniques including genetic calcium indicators and two-photon imaging to analyze neuronal...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Illinois a $109,076 Project Grant on January 25, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate ovarian steroid mechanisms underlying female cannabis use patterns. The research project, which runs through January 24, 2030, examines the causal relationship between menstrual cycle hormone fluctuations—specifically progesterone and estradiol—and cannabis use...
Oklahoma State University Center for Health Sciences is conducting research on the sex-specific role of sumoylation in heroin seeking under a $377,586 Project Grant award from the National Institute on Drug Abuse (NIDA), Drug Use and Addiction Research Programs (CFDA 93.279). The research project, active from February 15, 2026, through January 31, 2028, investigates how post-translational modifications mediated by the enzyme UBC9 influence heroin-seeking behavior and the neurobiological mechanisms underlying opioid use disorder. The study addresses a critical public health gap by examining sex-dependent differences in neuroadaptations, particularly the heightened susceptibility of females to opioid craving and relapse compared to males. The research deliverables include empirical findings on sex-specific sumoylation patterns in the nucleus accumbens brain region and how these modifications affect heroin-induced behavioral changes and target protein functionality. The project builds upon preliminary data demonstrating different sumoylation profiles between sexes and the role of ovarian hormones in drug-taking behavior, with aims to develop a more comprehensive understanding of long-term neuroadaptations that can inform therapeutic development for heroin use disorder. Research will be conducted at the award recipient's facility in Tulsa, Oklahoma.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $377.6k | 2/12/26 |