Project Grant R21CA304863
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded the University of Hawaii at Manoa a Project Grant totaling $402,401 under the Cancer Treatment Research program (CFDA 93.395) effective May 1, 2026, through April 30, 2028. This award supports translational exploratory research investigating the therapeutic targeting of upregulated BAP1 (BRCA1-associated protein 1) in hepatocellular carcinoma (HCC). The project addresses a critical clinical gap: while immunotherapy...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a $681,676 Project Grant to the University of Southern California under the Cancer Cause and Prevention Research program (CFDA 93.393) effective April 1, 2026, through March 31, 2031. This translational research project investigates per- and polyfluoroalkyl substances (PFAS) as novel risk factors for hepatocellular carcinoma (HCC) by integrating population-based epidemiological research with mechanistic laboratory studies....
- Federal Grant Award Summary The National Cancer Institute awarded the University of Hawaii at Manoa a $402,400 Project Grant under the Cancer Treatment Research program (CFDA 93.395) for research investigating neutrophilic myeloid-derived suppressor cells (PMN-MDSCs) as an immunotherapy target in hepatoblastoma. The grant, effective from May 15, 2025 through April 30, 2027, will deliver preclinical research combining innovative mouse genetic approaches with therapeutic studies to determine how...
- Federal Grant Award Summary The University of Hawaii at Manoa received a $663,930 Project Grant from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396), effective August 1, 2026 through July 31, 2031. The award supports research into novel biomarkers for predicting and improving immunotherapy response in non-small cell lung cancer (NSCLC). The project will deliver two primary products: (1) development and clinical validation of a laboratory test based on an...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Institute for Cancer Research a $766,439 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) effective April 1, 2026, through March 31, 2031. This research initiative investigates intratumor heterogeneity as a predictor of clinical outcomes in bladder cancer patients pursuing cystectomy avoidance strategies. The project focuses on analyzing how endogenous mutagenic processes (specifically...
- Federal Grant Award Summary The National Cancer Institute awarded a $248,998 Project Grant to Massachusetts General Hospital on September 16, 2025, under the Cancer Treatment Research program (CFDA 93.395) to support research titled "Integrating a Multi-Omics Cohort Study with a Medically Tailored Meal Intervention to Target Ultra-Processed Foods for Colorectal Cancer Prevention and Control." The award, which extends through August 31, 2028, funds a two-phase research initiative...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded the University of Miami's Office of Research Administration – School of Medicine a $254,333 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) effective September 23, 2025, with completion by August 31, 2027. This award funds research investigating racial disparities in breast cancer risk and gene expression, specifically examining the roles of genetic and lifestyle factors. The...
- Federal Grant Award Summary Award Details: Funding Agency: National Cancer Institute Federal Grant Program: Cancer Cause and Prevention Research (CFDA 93.393) Award Amount: $460,254 Award Date: July 16, 2026 Completion Date: June 30, 2028 Awardee: HMH Hospitals Corporation (Hackensack University Medical Center), Edison, NJ Research Products and Services: This Project Grant supports basic and translational research aimed at identifying predictive and prognostic adipome biomarkers in obese...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $698,212 Project Grant to the University of Cincinnati's Sponsored Research Services Division on April 1, 2026, under the Environmental Health program (CFDA 93.113). The award funds a research initiative examining the impact of micro- and nanoplastics (MNPs) on cardiovascular health and disease. The project delivers mechanistic and translational research products utilizing both in vivo...
- Federal Grant Award Summary The National Cancer Institute awarded a $425,573 Project Grant to Magee-Womens Research Institute and Foundation under the Cancer Treatment Research program (CFDA 93.395) for the period of July 1, 2025 through June 30, 2027. The grant funds research to identify specific gut bacteria species, metabolites, and metabolic pathways associated with mammographic breast density (MBD) as a modifiable risk factor for breast cancer prevention. The research will employ...
The National Cancer Institute awarded a $402,401 Project Grant to the University of Hawaii at Manoa on July 16, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393). The award supports research investigating microplastics (MP) and nanoplastics (NP) exposure and their relationship to obesity within the Multiethnic Cohort (MEC) Adiposity Phenotype Study. This research is being conducted in response to PAR-21-341, "Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)," and will continue through June 30, 2028. The project focuses on mechanistic and epidemiological research into human exposure to microplastics and nanoplastics as potential carcinogenic or metabolic risk factors, with specific attention to adiposity phenotypes and obesity outcomes. The work aligns with the Cancer Cause and Prevention Research program's objectives to identify cancer risks, risk reduction strategies, and mechanistic factors contributing to cancer development in humans, particularly through investigation of environmental exposures and their health impacts in a diverse multiethnic population.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $402.4k | 7/16/26 |