This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA program 93.846 Arthritis, Musculoskeletal and Skin Diseases Research provides $715,957 to support research into the mechanisms by which type I interferon promotes the expansion of T peripheral helper (Tph) cells in patients with systemic lupus erythematosus (SLE). The 5-year project, which runs from March 2025 through February 2030, will apply cutting-edge...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $550,909 to the University of Pittsburgh for a 5-year research project from Jul 2024 to Jun 2029. The research aims to understand the intrinsic and extrinsic factors regulating competition for active transforming growth factor beta (TGFβ) that promote skin-resident memory CD8 T cell...
This federal Project Grant award of $147,400.00 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant will fund research at Yale University to investigate how antigen non-related CD4+ T lymphocytes contribute to the pathogenesis of skin fibrosis in systemic sclerosis (scleroderma) and graft-versus-host disease. The research aims to characterize bystander...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $223,080 Project Grant (R21AR084632) to the Icahn School of Medicine at Mount Sinai to investigate the role of netrin signaling in regulating muscle stem cell quiescence and activation. This research, conducted under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to determine how netrin-1 signaling through the netrin receptors neogenin and DCC influences muscle...
The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $163,514 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to Brigham & Women's Hospital Inc. in Boston, MA. The grant, awarded on July 1, 2024, supports research to biochemically define a new G protein-coupled receptor (GPCR) signaling pathway with relevance to chemokine signaling and T cell function. The principal investigator, with mentorship...
This Project Grant award, with a total funding amount of $405,350.00, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant supports research to characterize lipid droplets in macrophage subsets and determine if targeted modulation of lipid droplets can shift macrophage function in the context of systemic lupus erythematosus (SLE). The research aims to...
The federal Project Grant award R01AR084518, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research into the role of autoantibodies targeting membrane repair proteins in the development and progression of idiopathic inflammatory myopathies (IIM), also known as myositis. The $926,078 award to The Ohio State University will fund 3 specific aims: 1)...
This federal Project Grant award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to study whether remote characterization of frequent gene/module expression can identify distinctive dynamics of inter-individual variations in the blood transcriptional trajectories following treatment with TNF inhibitors and IL-17 inhibitors in early psoriatic arthritis. The...
This federal Project Grant award, valued at $551,685.00, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports research at Duke University to investigate the roles of desmosomes, which are cell adhesion structures, in regulating the localization and translation of mRNAs. The project aims to determine the molecular mechanisms underlying the...
This federal Project Grant award, valued at $242,310.00, was awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports research at Rockefeller University to investigate the long-term impacts of allergic "type 2" skin inflammation on epithelial stem cells, which play a key role in tissue repair and adaptation. Specifically, the research aims to...