Project Grant R21AI200215
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $715,894 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 8, 2025, for a five-year research initiative extending through July 31, 2030. This award funds fundamental biomedical research investigating the influence of microbial metabolites on mitosome function in Cryptosporidium parvum, a parasitic pathogen...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Illinois a Project Grant totaling $736,822 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period February 1, 2026, through January 31, 2031. This award supports investigator-initiated biomedical research examining bacterial lipases and adaptation to the host lipid environment, with performance at the Chicago, Illinois campus. The research...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Illinois a Project Grant totaling $186,711 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated basic science research on polyamine biosynthesis regulation in Salmonella typhimurium. The research, performed at the University of Illinois location in Urbana, Illinois, and scheduled for completion by March 31, 2028,...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park a $749,353 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, through March 31, 2031. This award funds investigator-initiated biomedical research to elucidate the cellular and molecular mechanisms of Cryptococcal Immune Reconstitution Inflammatory Syndrome (IRIS), a life-threatening condition...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $1,529,898 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 6, 2025, through May 31, 2030. This award supports fundamental research to elucidate the biosynthesis of beta-1,6-glucan in the cell wall of Cryptococcus neoformans, a fungal pathogen responsible for approximately 150,000 deaths annually, particularly among...
- Federal Project Grant Award Summary The University of Pennsylvania received a $109,076 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective January 23, 2026, through August 31, 2029. This research grant supports investigator-initiated biomedical research focused on understanding T cell trafficking mechanisms in cryptosporidium infection. The project employs novel molecular tools...
- Federal Grant Award Summary The University of Illinois received a $154,052 Project Grant award dated August 5, 2025, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, entitled "Role of Arginine as a Metabolic Cue During Enteric Infection," will be conducted in Illinois through July 31, 2027. The award supports investigator-initiated biomedical research aimed at...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $451,000 Project Grant to the University of Chicago effective June 17, 2025, through May 31, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award funds investigator-initiated biomedical research focused on understanding how retroviruses, specifically Mouse Mammary Tumor Virus (MMTV), manipulate antibody responses and evade host protective immunity. The...
- Federal Grant Award Summary The University of Illinois received a $582,350 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 8, 2025, with completion targeted for June 30, 2030. The grant funds investigator-initiated research to identify microbiota-mediated colonization resistance mechanisms against Acinetobacter baumannii, a multidrug-resistant pathogen that poses...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $107,542 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period September 1, 2025, through August 31, 2027. The award supports investigator-initiated biomedical research examining the differential sorting and trafficking mechanisms of Plasmodium falciparum secreted proteins, with particular focus on how...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Illinois a Project Grant of $226,768 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research titled "Role of Cryptosporidium Effectors in Host Actin Manipulation." The award, effective May 5, 2026 through April 30, 2028, supports investigator-initiated biomedical research to advance understanding of how the parasitic protozoan Cryptosporidium manipulates host cell machinery during infection. This research directly addresses a critical public health gap, as Cryptosporidium remains a leading cause of severe diarrheal disease in young children and immunocompromised individuals, with currently no effective vaccines or therapeutic treatments available. The project delivers scientific research products through a combination of molecular genetics, cell biology, and in vivo animal infection studies conducted at the University of Illinois in Urbana. The research focuses on identifying and characterizing Cryptosporidium secretory effector proteins responsible for manipulating host actin polymerization during parasite invasion and niche establishment. Deliverables include experimental findings on the role of candidate parasite proteins and their interactions with host cellular machinery, contributing to improved understanding of Cryptosporidium biology and host-parasite interactions that may inform future vaccine and therapeutic development strategies.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $226.8k | 5/7/26 |