Project Grant R21AI196703
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of North Carolina at Chapel Hill $229,714 on April 13, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support innovative research investigating RNA ribosylation's role in viral RNA biology and innate immunity. The project, with a completion date of March 31, 2028, will advance scientific understanding of how post-transcriptional RNA...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of North Carolina at Chapel Hill a Project Grant totaling $553,779.00 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 4, 2026, with a completion date of January 31, 2031. This five-year research initiative investigates translation regulation mechanisms during human cytomegalovirus (HCMV) infection, focusing on how infected cells...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $233,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on May 13, 2025, with completion targeted for April 30, 2027. This award supports the development and characterization of self-circulating non-replicating bacteriophages (SCNRPVs) as a novel gene therapy platform for targeted...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $2.94 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on August 18, 2025, with a completion date of July 31, 2029. This award supports the development and clinical advancement of ACE2 immunodecoys as long-lasting immunoprophylaxis against sarbecoviruses and merbecoviruses that target...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $421,067 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on August 8, 2025, with a completion date of July 31, 2027. This research initiative delivers scientific investigation and experimental research services focused on understanding the mechanisms by which neutrophil extracellular traps...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $427,625 to the University of North Carolina at Chapel Hill on July 24, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research addressing the ethical, legal, and social implications (ELSI) of human viromics research. The grant extends through June 30, 2027, and represents NIAID's commitment to integrating bioethics work with genomic research in...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $190,825 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 10, 2026, with completion targeted for January 31, 2028. This award supports research applying novel genomic and bioinformatic tools to distinguish Plasmodium vivax malaria relapses from re-infections in clinical trial...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of North Carolina at Chapel Hill $420,553 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop novel single-cell measurement technologies and conduct fundamental research on antibiotic tolerance in bacterial populations. The award, effective August 8, 2025 through July 31, 2027, funds the design and implementation of a single-cell technique capable...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $427,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2027. This award supports research investigating antibiotic treatment failure in hypervirulent Klebsiella pneumoniae (HVKP) liver abscesses. The research project will deliver scientific outputs examining...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of North Carolina at Chapel Hill a Project Grant of $162,000 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 22, 2025, with completion anticipated by July 31, 2027. This award supports investigator-initiated research focused on understanding the mechanisms and parameters controlling gene amplification that leads to phenotypic...
The University of North Carolina at Chapel Hill received a $229,360 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded on April 15, 2026, with a completion date of March 31, 2028. This exploratory R21 grant funds research investigating the impact of host genetic variants on Chikungunya virus (CHIKV)-induced disease outcomes. The project delivers scientific research products focused on identifying and validating specific causal genes that regulate susceptibility to CHIKV-induced joint swelling and arthritis, utilizing the Collaborative Cross (CC) mouse genetic reference population to model human genetic diversity in disease response. The research outputs include genetic mapping studies designed to identify quantitative trait loci regulating CHIKV disease susceptibility and validation of candidate genes responsible for disease resistance. Specifically, the project aims to characterize the causal gene(s) underlying the HRCHK1 locus on chromosome 8 and identify genetic factors conferring extreme disease resistance in the CC026 mouse strain. These research activities advance fundamental knowledge of host-pathogen interactions and genetic determinants of infectious disease severity, with potential translational applications for understanding human CHIKV disease variation and informing future therapeutic interventions.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $229.4k | 4/17/26 |