Project Grant R21AI196365
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $498,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 7, 2025, with completion targeted for July 31, 2030. This award funds investigative research examining the role of a novel fungal RNA molecule, termed fungal stimulatory RNA (FSRNA), in modulating intestinal innate...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $616,588 to The Regents of the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 6, 2025, for a project completion date of May 31, 2030. This Project Grant funds research to illuminate environmental sensing mechanisms in Cryptococcus neoformans, the primary causative agent of fungal meningitis responsible for over 100,000...
- Federal Project Grant Award Summary The University of Texas MD Anderson Cancer Center received a $152,097 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 1, 2025, through August 31, 2030. The award supports preclinical research aimed at developing innovative immunomodulatory therapies to combat post-viral aspergillus pneumonias—deadly secondary mold infections that...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded J. Craig Venter Institute, Inc. a Project Grant totaling $556,375 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 23, 2025, with a completion date of June 30, 2027. This research initiative focuses on identifying the molecular determinants governing thermoadaptation and parasitic growth of Histoplasma capsulatum, a dimorphic fungal pathogen responsible...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital a $489,500 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2027. This award funds research to identify and characterize novel antifungal drug targets in Candida albicans, a major causative agent of invasive fungal infections in immunocompromised patients. The project focuses on...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $116,022 to the University of Texas Health Science Center at San Antonio under the Allergy and Infectious Diseases Research program (CFDA 93.855) on May 20, 2025, with a completion date of November 30, 2025. This project grant funds research investigating the SARS-CoV-2 main protease (Mpro) dimerization mechanism, a critical enzymatic function required for viral replication and pathogenesis. The...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a Project Grant totaling $520,128 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2030. This research project investigates molecular mechanisms by which Ehrlichia chaffeensis, a tick-borne pathogenic bacterium, manipulates host cell RNA splicing factors to evade innate...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Massachusetts Medical School $1,193,457 on July 21, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop fungal antigen resources for vaccine and diagnostic development. This project grant, which extends through June 30, 2030, addresses a critical gap in public health by producing, validating, and providing defined immunogenic fungal...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $440,000 to the University of Texas Medical Branch at Galveston under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 3, 2025, for a project period extending through June 30, 2027. This Project Grant supports biomedical research investigating the function and mechanism of long non-coding RNA CHAST (lncRNA CHAST) in Trypanosoma cruzi infection and Chagas disease...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Tennessee Health Science Center a Project Grant of $121,752 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective November 1, 2025, with completion targeted for April 14, 2027. This award supports investigator-initiated research focused on interrogating the SIDB-dependent septation pathway to enhance echinocandin antifungal efficacy in treating...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Health Science Center at Houston $429,000.00 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a Project Grant beginning February 2, 2026, with completion targeted for January 31, 2028. The primary deliverable is the development and application of spatial transcriptional analysis technology to study host-pathogen interactions in fungal infections, specifically examining how host tissue microenvironments influence virulence gene expression in Candida albicans. The grant supports the establishment of a platform that enables single-cell resolution visualization and quantification of fungal messenger ribonucleic acid (mRNA) molecules in infected tissue samples. This technology addresses limitations of traditional bulk gene expression analysis by capturing cell-to-cell variability and spatial configuration of infection sites. The research outputs will advance understanding of fungal cell heterogeneity during mammalian host colonization and infection, generating foundational knowledge applicable to pathogenesis research and potentially informing development of more targeted therapeutic interventions against fungal infections.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $429.0k | 1/30/26 |