Project Grant R21AI195434
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases awarded The Johns Hopkins University a Project Grant of $427,438 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2028. This research initiative focuses on identifying and eliminating antigen-specific expanded clones of latently infected CD4+ T cells to reduce the HIV reservoir. The research leverages an observation from an elite...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $779,616 Project Grant (CFDA 93.855: Allergy and Infectious Diseases Research) effective April 10, 2026, through March 31, 2031, to conduct research characterizing the defective human immunodeficiency virus type 1 (HIV-1) proviral reservoir in children and adolescents with perinatal HIV-1 infection. The research leverages biobanked peripheral blood mononuclear cell...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $672,248 Project Grant (CFDA 93.855 – Allergy and Infectious Diseases Research) on September 15, 2025, to conduct a comprehensive five-year research initiative examining HIV reservoir dynamics and immune responses across the female reproductive lifespan. Led by co-principal investigators Dr. Eileen Scully (Johns Hopkins University) and Dr. Ronald Galiwango (Rakai...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $145,299 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025 through July 31, 2029. This award supports the development of novel Bayesian causal structural discovery and reinforcement learning methods to advance precision medicine in HIV care, specifically addressing the challenge of designing...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant of $765,422 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 17, 2026, with completion scheduled for March 31, 2031. This research initiative focuses on investigating the mechanisms of antigen diversification in Trypanosoma brucei, a parasitic protozoan responsible for significant public health challenges in...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $709,891 Project Grant on August 1, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support a five-year research project extending through July 31, 2030. The award funds structural and mechanistic research on the polar tube invasion apparatus of microsporidian parasites, unicellular fungal pathogens that cause opportunistic...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a Project Grant totaling $1,285,304 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and evaluate an enhanced HIV vaccine regimen capable of producing durable broadly neutralizing antibody (BNAB) responses. The research, which commenced August 1, 2025, and extends through July 31, 2030, leverages a novel six-shot germline-targeting...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $803,591.00 Project Grant to the University of Pennsylvania on February 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The five-year research initiative, concluding January 31, 2031, focuses on developing SHIV-infected rhesus macaque models to advance HIV-1 broadly neutralizing antibodies (BNAbs) development. The research will produce monoclonal antibodies...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $368,750 to the Veterans Medical Research Foundation of San Diego under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 10, 2025, for a project period extending through June 30, 2030. This Project Grant funds biomedical research investigating the mechanisms by which HIV-1 and HIV-2 antagonize BST2/tetherin, an interferon-stimulated gene with potent antiviral...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $475,681 Project Grant to the University of Wisconsin–Madison under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period February 1, 2026, through January 31, 2031. The award supports the development and validation of novel molecular and cellular tools to investigate HIV-1 alternatively spliced transcript functionality. The primary deliverable is a suite of...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $247,125 Project Grant effective May 21, 2026, through April 30, 2028, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research focused on isolating and characterizing monoclonal antibodies (MAbs) against the HIV-1 antisense protein ASP (Antisense Protein) derived from people living with HIV-1, including elite controllers, viremic controllers, and individuals both on and off antiretroviral therapy. The research will involve functional testing of isolated MAbs through in vitro and ex vivo assays to investigate ASP's role in HIV-1 infection and viral entry mechanisms. The study will be conducted in Baltimore, Maryland, in collaboration with the Institute of Human Virology at the University of Maryland School of Medicine. This research addresses a critical gap in understanding HIV-1 pathogenesis by focusing on ASP, a conserved protein found in pandemic HIV-1 Group M strains that facilitates viral entry and demonstrates variable presence in individuals with differential disease progression. By isolating and characterizing functional antibody responses to ASP, this project aims to generate scientific knowledge that could inform development of novel therapeutic and vaccine strategies targeting HIV-1 infection.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $247.1k | 5/25/26 |