Project Grant R21AI194031
- This $153,169 federal Project Grant award from the National Institutes of Health (CFDA 93.310 Trans-NIH Research Support program) to The Ohio State University aims to develop a rapid, non-invasive method for assessing radiation exposure using Raman spectroscopy and artificial intelligence. The project will collect and analyze hair samples from mice exposed to controlled radiation doses to develop models for detecting exposure greater than 2 Grays and differentiating higher doses above 5 Grays....
- This $157,400 federal Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) is funding the development of an artificial intelligence (AI)-powered cytogenetic biodosimetry platform to rapidly detect chromosomal aberrations for radiation triage following radiological or nuclear incidents. The award to the Georgia TECH Research Corp, doing business as the Office of Sponsored Programs, will leverage...
- The National Institutes of Health (NIH) awarded a $350,000 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) to The Medical College of Wisconsin, Inc. to deliver a field-ready, physically-based biodosimetry device capable of accurately estimating radiation doses in the range of 0-10 Gy within 0.5 Gy and estimating the homogeneity of irradiation exposure using in vivo measurements of human nails. The project aims to enhance biodosimetry capabilities by improving...
- The U.S. Department of Health and Human Services National Institutes of Health (NIH) awarded a $156,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to The Medical College of Wisconsin, Inc. The overall objective of this 2-year project, from August 1, 2025 to July 31, 2027, is to develop a panel of biomarkers that can discriminate between exposure of upper- and lower-body organs to radiation and predict health outcomes. The research aims to identify organ-specific...
- This Cooperative Agreement award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) provides $616,202 to Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare System Inc., to identify and develop non-invasive biomarkers of radiation exposure in human skin. The project aims to utilize a model of irradiating human skin grafts carried by immunodeficient mice to identify and validate keratinocyte biomarkers that can discriminate between...
- The National Institutes of Health (NIH) awarded a $156,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to Georgetown University on August 11, 2025. The project, titled "Development of a Multiomic Biodosimetry Panel for Use During Sepsis and Antibiotic Treatment", aims to develop a novel panel of metabolomic and gene expression biomarkers to rapidly screen and provide accurate dose reconstruction for individuals exposed to ionizing radiation. This panel will...
- This federal Cooperative Agreement award from the National Institutes of Health (NIH) Trans-NIH Research Support Program (CFDA 93.310) provides $551,250 to the University of California, Los Angeles (UCLA) to develop a novel radiation biodosimeter using autofluorescence imaging. The goal is to determine if radiation-induced autofluorescence can be used as a surrogate for radiation dose and to assess the extent of damage to predict lethality from acute radiation syndrome. The project will...
- The U.S. Department of Health and Human Services, National Institutes of Health (NIH) awarded a $155,857 Project Grant under the Trans-NIH Research Support (CFDA 93.310) program to Signablok, Inc. in Massachusetts. The funding supports the development of a novel medical countermeasure to mitigate potentially lethal acute radiation syndrome (ARS). The project aims to create a well-tolerable and effective first-in-class therapeutic that can be administered at least 24 hours post-radiation exposure...
- This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) provides $159,000.00 to the University of Pittsburgh to research inhibition of the tyrosine kinase FGR as a potential medical countermeasure to mitigate hematopoietic acute radiation syndrome (H-ARS). The research aims to establish FGR as a master regulator of bone marrow inflammation following total body irradiation, and demonstrate that inhibiting FGR can improve bone marrow...
- This Project Grant award from the Department of Health and Human Services National Institutes of Health (CFDA 93.310 Trans-NIH Research Support program) is focused on investigating the use of gaseous molecules, specifically xenon, as medical countermeasures to mitigate and treat radiation-induced skin injury. The $155,083 award will fund in vitro studies to assess the ability of xenon gas to regulate oxidative stress, reduce inflammation, and limit cellular senescence in human skin cells exposed...
This Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) aims to develop a non-invasive, painless biodosimeter using Fourier transform infrared attenuated total reflection (FTIR-ATR) imaging and statistical machine learning. The $197,930 award will fund research to expand upon preliminary data showing FTIR-ATR imaging can distinguish irradiated from control mice at doses as low as 0.1 Gray. The project will focus on validating this signature in human skin explants and identifying the underlying biomolecular changes. This novel, non-invasive procedure has the potential to enable deployable imaging devices for biodosimetry at population scales, benefiting radiobiology, epidemiology, and radiation exposure monitoring efforts.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $197.9k | 9/16/25 |