Project Grant R21AI191113
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Pennsylvania State University a $247,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective May 1, 2026, through April 30, 2028. This award funds investigator-initiated research focused on understanding the molecular mechanisms controlling gene expression in Plasmodium parasites during the critical transition period from mammalian host to...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Pennsylvania State University a Project Grant totaling $235,950 (awarded May 1, 2026; completion date April 30, 2028) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research initiative, "Engineering Artificial Endosymbiosis in Mosquitoes Using Synthetic Biology First Principles," focuses on developing foundational knowledge and experimental...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Pennsylvania State University a $842,720 Project Grant on April 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop statistical models for estimating spatial and sub-population HIV epidemics. The project, which runs through March 31, 2031, addresses critical gaps in HIV epidemiological data that impede effective global response efforts. The research...
- Federal Grant Award Summary Pennsylvania State University, operating as Penn State Milton S. Hershey Medical Center, received a $267,704 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded April 3, 2026, with completion targeted for March 31, 2028. The grant funds development and deployment of a point-of-care lateral flow diagnostic device for rapid detection of Paenibacillus...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of South Florida a Project Grant of $203,060 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, with completion targeted for March 31, 2028. The research project, titled "Ecology of Plasmodium Malariae Transmission in Cameroon," will deliver epidemiological surveillance and vector ecology data to advance understanding of...
- Federal Grant Award Summary The Pennsylvania State University received a $385,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 7, 2025, with completion targeted for June 30, 2027. The project focuses on developing and evaluating novel inducible nitric oxide synthase (iNOS) and nitric oxide (NO) inhibitors designed to mitigate inflammatory cell death, acute respiratory...
- Federal Grant Award Summary The University of Pennsylvania received a $434,375 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, with a completion date of July 31, 2027. This research project will investigate retroelement-mediated cis-regulation of embryonic hematopoiesis, specifically examining how retrotransposon-derived long terminal repeats function as...
- Federal Project Grant Award Summary The University of Pennsylvania received a $822,015 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 6, 2025, with a completion date of July 31, 2026. The grant funds the development of novel statistical methodologies to address critical methodological challenges in infectious disease research, specifically causal identification theory...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $451,000 to the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 15, 2025, with completion scheduled for July 31, 2027. This Project Grant supports the development and application of high-resolution phage immunoprecipitation sequencing (PhIP-Seq) arrays designed to comprehensively evaluate antibody responses to...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, Baltimore $445,488 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period from July 1, 2025 through June 30, 2027. This Project Grant supports scientific research to characterize long non-coding RNAs (lncRNAs) in Plasmodium falciparum and elucidate their roles in gene regulation. The research deliverables include...
The Pennsylvania State University received a $196,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on May 19, 2026, with a completion date of April 30, 2028. This research project, titled "Harnessing Single-Cell Transcriptomics for the Determination of Sexual Dimorphism During Plasmodium falciparum Gametocytogenesis," focuses on elucidating the molecular mechanisms governing sexual development and differentiation in the malaria parasite P. falciparum using advanced single-cell RNA sequencing (scRNA-seq) technologies. The primary deliverables of this award include comprehensive transcriptional analysis of the gametocytogenesis developmental process—the 12-day sexual stage critical for malaria transmission to mosquito vectors—utilizing the 10X Genomics Chromium platform with Illumina short-read sequencing. The research employs P. falciparum strains from geographically diverse locations and genetically modified mutants to identify the temporal dynamics and regulatory mechanisms of sex-specific cell fate determination. By addressing significant knowledge gaps regarding the timing and regulation of sexual dimorphism in this parasitic organism, this research is intended to advance understanding of fundamental parasitic biology with potential implications for malaria transmission control and intervention strategies.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $196.6k | 5/20/26 |