Project Grant R21AI193463
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Pennsylvania State University a $247,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning May 1, 2026 and concluding April 30, 2028. This research initiative applies advanced reverse genetic, transcriptomic, proteomic, and microscopy-based approaches to investigate the mechanisms of translational repression control in Plasmodium parasites...
- Federal Grant Award Summary The Pennsylvania State University received a $385,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 7, 2025, with completion targeted for June 30, 2027. The project focuses on developing and evaluating novel inducible nitric oxide synthase (iNOS) and nitric oxide (NO) inhibitors designed to mitigate inflammatory cell death, acute respiratory...
- Federal Grant Award Summary The Pennsylvania State University received a $842,720 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 2, 2026, with completion scheduled for March 31, 2031. The award supports the development of statistical models and methodologies to estimate spatial and sub-population HIV epidemics, addressing critical information gaps in the global HIV...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant totaling $267,704 to Pennsylvania State University, doing business as Penn State Milton S. Hershey Medical Center, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award, effective April 3, 2026 through March 31, 2028, funds the development and deployment of a lateral flow point-of-care diagnostic device for rapid detection of Paenibacillus...
- Federal Project Grant Award Summary The University of Pennsylvania received a $3.20 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 24, 2025, with a completion date of June 30, 2029. This research project will define the molecular and cellular mechanisms of non-canonical inflammasome responses to lipopolysaccharide (LPS) in both mouse and human models. The...
- Federal Grant Award Summary The University of Pennsylvania received a $480,249 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2027. This award supports research investigating the extracellular matrix (ECM) as a determinant of filovirus infectivity, specifically examining how ECM composition and stiffness influence Ebola virus (EBOV) and Marburg...
- Federal Project Grant Award Summary The University of Pennsylvania received a $109,076 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective January 23, 2026, through August 31, 2029. This research grant supports investigator-initiated biomedical research focused on understanding T cell trafficking mechanisms in cryptosporidium infection. The project employs novel molecular tools...
- Federal Project Grant Award Summary The University of Pennsylvania received a $822,015 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 6, 2025, with a completion date of July 31, 2026. The grant funds the development of novel statistical methodologies to address critical methodological challenges in infectious disease research, specifically causal identification theory...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Trustees of The University of Pennsylvania a Project Grant totaling $627,483 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2031. The research project, titled "Elucidating How Environmental Perturbations Determine the Duration of Enteric Viral Infection," will investigate fundamental mechanisms underlying...
- Federal Grant Award Summary The University of Pennsylvania received a $434,375 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, with a completion date of July 31, 2027. This research project will investigate retroelement-mediated cis-regulation of embryonic hematopoiesis, specifically examining how retrotransposon-derived long terminal repeats function as...
The Pennsylvania State University received a $235,950 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 1, 2026 through April 30, 2028. The project, "Engineering Artificial Endosymbiosis in Mosquitoes Using Synthetic Biology First Principles," focuses on developing a synthetic biology system to study obligate endosymbionts—microorganisms that live within eukaryotic cells—in mosquito hosts. The research addresses a critical gap in understanding the functional biology of endosymbionts that cannot be cultured or manipulated in laboratory settings, with applications to arbovirus transmission control in mosquito populations. The primary deliverable is the development of scientific knowledge and methodological approaches to characterize what constitutes a functional symbiont and enable manipulation of obligate endosymbionts for applied translational purposes. By establishing techniques to study endosymbiont biology in mosquitoes, the project aims to move beyond reliance on naturally occurring strains and support the optimization of symbiont-based biocontrol agents for disease vector management. The work will be conducted at Penn State's University Park campus in State College, Pennsylvania, contributing to NIAID's broader mission of supporting innovative research addressing urgent infectious disease challenges.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $236.0k | 5/1/26 |