Project Grant R21AI190884
- This federal Project Grant award of $743,817 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to delineate T cell receptor (TCR) families associated with protection from progression to pulmonary tuberculosis (TB) disease. The research will use advanced imaging techniques like fluorodeoxyglucose positron emission tomography and computed tomography (FDG PET-CT) to identify TB-exposed household...
- This Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $194,400 in funding to Brigham & Women's Hospital Inc. to conduct research on the role of antibody-dependent innate effector function in tuberculosis (TB) disease progression among individuals co-infected with HIV. The 5-year research program aims to comprehensively investigate how perturbations to...
- This $854,000 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), aims to assess post-tuberculosis (TB) lung disease in TB patients with and without HIV coinfection. The project will utilize novel positron emission tomography (PET) imaging techniques, such as 11C-rifampin PET, to longitudinally profile lesional characteristics and antibiotic exposures in animal models...
- The federal Project Grant award of $3,089,360 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports the development and evaluation of innovative tuberculosis (TB) diagnostic platforms and assays. The 5-year project, awarded to Rutgers, The State University of New Jersey, aims to accelerate promising TB diagnostics through a fast-paced pipeline that includes technology scouting, development...
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $212,636 to Socios En Salud Sucursal Peru, a non-profit healthcare organization in Peru. The grant supports the development of tools to help primary care physicians in low- and middle-income countries better identify child and adolescent tuberculosis (TB) household contacts who require further...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $536,148 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Tufts University School of Medicine to conduct research on integrating point-of-care urine isoniazid testing into routine tuberculosis (TB) care in India. The research aims to facilitate early and accurate identification of TB patients who are at risk of poor outcomes, including death and disease recurrence, due to...
- This $743,651 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to validate the use of plasma cell-free RNA (cfRNA) as a biomarker for the diagnosis of tuberculosis (TB) and monitoring of treatment. The grant will support the validation of cfRNA signatures in a large patient cohort of 1,378 adults across five countries, and the comparison of cfRNA diagnostic accuracy against...
- This $193,375 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to identify bacterial determinants that may contribute to variable treatment responses for tuberculosis (TB). The project, conducted by researchers at the Harvard T.H. Chan School of Public Health, aims to investigate the effects of clinically prevalent variants in the ESX1 secretion system on TB...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $446,875 to The Trustees of the University of Pennsylvania to evaluate the use of Fibroblast Activation Protein (FAP) Positron Emission Computed Tomography (FAP PET/CT) imaging to characterize lung fibrosis in adult pulmonary tuberculosis (TB) patients. The research aims to determine how changes in FAP radiographic...
- This $830,261 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research program) supports research on post-tuberculosis (TB) lung disease among individuals successfully treated for TB in Lima, Peru. The project, titled "Host- and Pathogen-Specific Risk Factors for Post-Tuberculosis Lung Disease among People Successfully Treated for TB in Lima, Peru: BEAT-PTLD," will evaluate 1,000 TB patients and 291 community...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research CFDA program, will support research to investigate the use of chest radiography (CXR) to identify young individuals with early stages of tuberculosis (TB) in a community-based active case-finding program in Lima, Peru. The $242,376 award to Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare System, will fund a 2-year study to evaluate whether CXR abnormalities in young individuals were associated with subsequent development of active TB disease, and to identify specific CXR features linked to incident active TB. This research aims to improve strategies for early identification and intervention of TB, which remains a significant global health challenge.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $242.4k | 9/23/25 |