This federal Project Grant award, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), is funding a $264,750 research initiative at the University of Washington. The project, titled "Integrin-Mediated Regulation of Type-1 Dendritic Cell Positioning and Function in Lymph Nodes," aims to elucidate the role of the CD11a integrin in regulating the positioning and cell-cell interactions of lymph node-resident dendritic cells (DC1). The research will investigate how this positioning impacts the transfer of tumor antigens between migratory and resident DC subsets, and the subsequent generation of anti-tumor CD8 T cell responses. By enhancing the understanding of cellular organization and crosstalk within lymphoid organs, this project has the potential to inform the development of novel immunotherapeutic strategies for cancer.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $264.8k | 4/23/25 |