Project Grant R21AG103973
- The National Institute on Aging, part of the Department of Health and Human Services, awarded the University of Notre Dame $582,492 on September 1, 2026, under the Aging Research program (CFDA 93.866) for Project Grant R61AG104103, OPENCARE: Open-Source Infrastructure for Evaluating Conversational AI in Dementia Care. The recipient will develop and deliver two open-source research infrastructures to address the absence of technical evaluation standards for conversational AI in Alzheimer's...
- The National Institute on Aging awarded the University of California, Berkeley $549,260 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop advanced large language model-based AI tools that enhance precision in predicting Alzheimer's disease pathology and cognitive outcomes. The research addresses critical gaps in precision medicine for Alzheimer's disease, particularly the need to capture patient heterogeneity, accurately identify treatment candidates for...
- The National Institute on Aging awarded $1.499 million to S-3 Research LLC on September 20, 2025, under the Aging Research program (CFDA 93.866) to develop a multi-modal digital tool improving diversity and inclusivity in Alzheimer's Disease and Related Dementias (ADRD) clinical trial participation. S-3 Research LLC will develop an integrated mobile application, website, and artificial intelligence chatbot designed to enhance education, recruitment, and enrollment of older adults in ADRD...
- The National Institute on Aging awarded the University of Southern California $359,735 on September 1, 2026, under the Aging Research program (CFDA 93.866) for a Project Grant (R21AG091332) to develop generative artificial intelligence methods for interpretable Alzheimer's disease detection using denoising diffusion probabilistic models applied to neuroimaging. The project addresses the challenge of distinguishing brain changes attributable to Alzheimer's disease from normal age-related...
- The National Institute on Aging, part of the National Institutes of Health, awarded $1,250,191 to the University of North Carolina at Chapel Hill on February 15, 2026, under the Aging Research program (CFDA 93.866) to develop an integrated artificial intelligence and experimental workflow for accelerating discovery of small-molecule modulators that influence Alzheimer's disease through microglial phagocytosis regulation. The funded work combines AI-driven computational methods with...
- The National Institute on Aging awarded Boston University Medical Campus $323,825 on January 1, 2026 under the Aging Research program (CFDA 93.866) to develop advanced artificial intelligence tools for early detection of Alzheimer's disease and related dementias using digital neuropsychological tests. The recipient will construct novel graph-based representations of digital clock drawing test (DCDT) drawings and build machine learning models to detect cognitive impairment. The work focuses on...
- The National Institute on Aging awarded Brain Research Africa Initiative $431,990 on February 1, 2026, under the Aging Research program (CFDA 93.866) to culturally adapt and validate a tablet-based multi-domain digital cognitive assessment tool for Alzheimer's disease and related dementias in Cameroon, and to develop and pilot infrastructure for improved dementia care and research. The project addresses the projected 300 percent increase in dementia prevalence across sub-Saharan Africa over...
- The National Institute on Aging awarded The Johns Hopkins University $680,637 on September 15, 2026, under the Aging Research program (CFDA 93.866) to conduct a pragmatic clinical trial improving cognitive impairment screening in older adults with diabetes. The funded work develops and validates novel tools using natural language processing and large language models to identify cognitive impairment and Alzheimer's disease and related dementias screening events in electronic health records. The...
- The National Institute on Aging awarded Duke University $4.899 million on August 15, 2026, under the Aging Research program (CFDA 93.866) to establish the Duke Artificial Intelligence and Technology Collaboratory for Aging: Governance and Evaluation (DUKE AITC-AIGE), a national initiative bridging the implementation gap between artificial intelligence research and its application in care for older adults and individuals with Alzheimer's disease and related dementias. The collaboratory operates...
- The National Institute on Aging awarded Carevirtue Technologies, Inc. $1.717 million on September 20, 2025, under the Aging Research program (CFDA 93.866) to develop an AI-enabled dementia care agent for rural Alzheimer's disease and related dementia (ADRD) care partners. Carevirtue will develop a 24/7 AI-enabled dementia care agent that integrates vetted ADRD caregiving education and support content from the National Institute on Aging, AgeUcate, and other authoritative sources into a large...
The National Institute on Aging awarded Clemson University $412,078 under the Aging Research program (CFDA 93.866) on September 1, 2026, to develop and evaluate large language model chatbots designed to enhance older adults' engagement in medical consultations about Alzheimer's disease and related dementias. The project will assess how LLM-based generative chatbots can provide personalized patient education about dementia, improve patient knowledge of ADRD, and augment patient-physician educational discussions. The research will establish foundational understanding of chatbot effects on healthcare conversations and patient comprehension, and identify optimal criteria for AI-based tool development to support effective, person-centered patient care. The award addresses misconceptions and stigma surrounding ADRD that discourage early diagnosis and complicate discussions about cognitive decline. Work is performed at Clemson University in Clemson, South Carolina, with a period of performance from September 1, 2026, through August 31, 2028. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $412.1k | 8/27/26 |