Project Grant R21AG101586
- Federal Grant Award Summary The University of California, San Diego received a $150,512 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on August 2, 2026, with a completion date of August 1, 2027. This award funds the development and validation of a novel diffusion magnetic resonance imaging (MRI) signature for early detection of Alzheimer's disease. The project addresses a critical public health need by advancing neuroimaging...
- Federal Project Grant Award Summary The University of California, San Diego received a $3.14 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) awarded September 15, 2025, with an ultimate completion date of August 31, 2029. This research project delivers comprehensive analysis and characterization of human brain neuropeptidomes and their biosynthetic proteases in normal and Alzheimer's disease (AD) conditions. The primary research...
- Federal Project Grant Award Summary The University of California, San Diego received a $439,750 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) for the period May 1, 2026 through April 30, 2028. This award funds research investigating the molecular mechanisms of nucleophagy—the autophagic degradation of nuclear envelope regions—and its relationship to chronological aging. The research will employ genetic screening, biochemical analysis, and...
- Federal Grant Award Summary The University of California, San Diego received a $700,795 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) for the period of February 1, 2026, through January 31, 2031. The award funds the development and deployment of REDCAT (Raman Enhanced Determination of Cell Atlas and Typing), an integrated research platform designed to map single-cell metabolic activity in complex tissues and identify transcriptional and...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of California, Santa Barbara $4.77 million on August 5, 2025, under the Aging Research program (CFDA 93.866) to conduct a four-year research initiative examining spatial navigation, sex hormones, and cognitive aging. The project will deliver comprehensive biomedical research investigating how endocrine changes during midlife—particularly the menopausal transition and associated declines in sex...
- Federal Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded a Project Grant of $182,173.00 to the University of California, San Diego, effective March 1, 2026, through February 28, 2031. This award supports research investigating noradrenergic modulation during sleep and its relationship to memory consolidation. The project delivers research outputs through computational modeling, multi-site electrophysiological recordings,...
- Federal Project Grant Award Summary The University of California, San Diego received a $165,488 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) effective March 1, 2026, through November 30, 2028. This project addresses critical diagnostic challenges in Alzheimer's Disease (AD), which affects millions of Americans and carries a high misdiagnosis rate of up to 25%, resulting in inappropriate treatments in 18-67% of cases. The grant supports the...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of California, Irvine a $3.22M project grant (CFDA 93.866, Aging Research program) on September 15, 2025, to investigate the role of the retrosplenial cortex (RSC) in Alzheimer's Disease (AD) pathogenesis. The research will be conducted through August 31, 2029, and will deliver scientific knowledge regarding the mechanisms by which neuronal hyperexcitability in the RSC contributes to AD-related...
- Federal Project Grant Award Summary The University of California, San Diego received a $437,375 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) for the period September 1, 2025 through August 31, 2027. The award funds biomedical research investigating NEK7 (NIMA-related kinase-7) as a potential suppressor of inflammation in aging hearts through regulation of RNA-binding proteins. The research addresses the critical connection between...
- Federal Grant Award Summary The University of California, San Francisco (UCSF) received a $109,084 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective August 15, 2025, through May 31, 2030. The award funds the Research in Alzheimer's Disease and Dementia (RADD) Summer Intern Program, developed and administered by UCSF's Science & Health Education Partnership. The program delivers annual research internship opportunities for five high...
The University of California, San Diego received a $439,750 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded on May 15, 2026, with a completion date of April 30, 2027. The grant supports a two-year research project investigating changes in hippocampal coding of very large spaces from adulthood to senescence. The research addresses a critical gap in understanding how the dorsal and ventral hippocampus contribute to spatial navigation and cognitive function in aging populations, with particular relevance to early detection and treatment of Alzheimer's disease. The project will characterize neural encoding patterns and animal behavior in large environments where ventral hippocampal place fields are functionally relevant, contrasting multi-field and multi-scale neural encoding across tasks of varying complexity. This research directly supports the National Institute on Aging's mission to advance understanding of age-related diseases and mechanisms of cognitive decline through biomedical research. By examining hippocampal structure and function during aging, the project aims to generate scientific knowledge regarding neurobiological mechanisms that could inform development of therapeutic interventions and diagnostic approaches for neurodegenerative disease prevention and treatment. The work will be conducted at UCSD's La Jolla, California campus, leveraging the institution's established research infrastructure and expertise in neuroscience and aging-related research.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $439.8k | 5/5/26 |