Project Grant R21AG098804
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $2,433,859 supports research at The Johns Hopkins University to investigate age-related hearing loss and cognitive decline. The key objectives are to study the molecular, cellular, and connectivity changes in the central auditory system during normal aging and Alzheimer's disease, with the goal of developing targeted therapeutic strategies. The research integrates single-cell sequencing,...
- The National Institute on Aging awarded Oregon Health & Science University $657,439 for basic research into synaptic and behavioral changes induced by hearing loss and Alzheimer's disease in the auditory brainstem, with funding obligated on March 1, 2026. The research investigates how auditory signal propagation is affected at different stages of Alzheimer's disease progression, with or without early-onset hearing loss, using mouse models that develop early-onset Alzheimer's (5XFAD) and...
- The National Institute on Aging awarded Applied Universal Dynamics, Corp $999,986 on September 20, 2025, under the Aging Research program (CFDA 93.866) to develop the SoundMind Smart Amplifier, an affordable, accessible hearing solution designed for persons with memory concerns and their family caregivers. Hearing loss and cognitive impairment frequently co-occur among older Americans, compounding effects on communication and social engagement. Only 30 percent of people with memory concerns...
- The National Institute on Aging awarded the University of Texas at Austin $10.686 million on September 15, 2025, under the Aging Research program (CFDA 93.866) to investigate remotely-supervised neuromodulation paired with language treatment for the logopenic variant of primary progressive aphasia, a progressive language disorder caused by underlying Alzheimer's disease pathology. The award supports research to enhance proven language treatment for LVPPA by combining it with tailored, home-based...
- The National Institute on Aging, part of the Department of Health and Human Services, awarded Vanderbilt University Medical Center $729,157 on September 4, 2026, under the Aging Research program (CFDA 93.866) to characterize age-specific communication and psychosocial outcomes in adults with cochlear implants across the adult lifespan. The project addresses a gap in understanding how age affects outcomes in cochlear implant recipients. Current clinical measures fail to capture the real-world...
- The National Institute on Deafness and Other Communication Disorders awarded the University of Wisconsin–Madison $201,890 on August 14, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to build epidemiological evidence addressing research gaps in hearing screening of older adults. The project will characterize the natural history of age-related hearing loss and identify optimal screening approaches by leveraging data from five longitudinal...
- The National Institute on Deafness and Other Communication Disorders awarded the University of South Florida $164,329 on September 16, 2025, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to conduct parallel human and animal studies examining associations between extended high frequency hearing loss, speech-in-noise performance, and cognitive decline in aging populations. The funded research encompasses two coordinated aims. Aim 1 involves assessment...
- The National Institute on Aging awarded the University of Texas at Austin $650,447 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop a profile-based framework for matching transitional care services to distinct patient-caregiver groups among persons living with dementia (PLWDs). The award funds research to identify patient-caregiver profiles and co-develop provider and system implementation tools that enable tailored, evidence-based transitional care delivery across...
- The National Institute on Aging awarded The Johns Hopkins University $680,637 on September 15, 2026, under the Aging Research program (CFDA 93.866) to conduct a pragmatic clinical trial improving cognitive impairment screening in older adults with diabetes. The funded work develops and validates novel tools using natural language processing and large language models to identify cognitive impairment and Alzheimer's disease and related dementias screening events in electronic health records. The...
- The National Institute on Aging awarded the University of Houston System $727,093 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop a community-engaged translational research network advancing Spanish-language neuropsychological assessment tools for cognitive aging and Alzheimer's disease research. The project, titled "Development of a Community Engaged Translational Research Network to Advance Spanish-Language Neuropsychological Assessment in Cognitive Aging...
The National Institute on Aging awarded the University of Texas Health Science Center at Houston $429,000 on September 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a developmental research project estimating the effectiveness of hearing aid initiation in reducing incident Alzheimer's disease and related dementias among older adults. The recipient will use target trial emulation with real-world data from the Texas All-Payor Claims Database to assess hearing aid effectiveness in reducing dementia incidence and examine potential differences by age, sex, and pre-existing cardiovascular disease. The study addresses a gap in randomized controlled trial evidence by leveraging claims data covering nearly all insured Texans, including Medicaid and Medicare Advantage enrollees eligible for hearing aid coverage. The project runs through August 31, 2028, with place of performance in Houston, Texas. The assistance type is a Project Grant, classified as R21 (exploratory/developmental research).
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $429.0k | 8/27/26 |