Project Grant RF1AG085565
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $856,024 to the University of Texas at Austin to develop and evaluate a comprehensive, multicomponent treatment protocol for individuals with speech/language-led dementias, such as primary progressive aphasia (PPA). The intervention, termed "Multi-PA", aims to address the communication challenges faced by PPA patients across varying stages of disease severity. It integrates...
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA program "Research Related to Deafness and Communication Disorders" (93.173), will fund a clinical trial to investigate the use of transcranial direct current stimulation (tDCS) and attention-focused language treatment to improve attention, language, and reduce post-stroke fatigue in individuals with aphasia. The total award amount is $760,283, with a project period...
- This $310,000 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research by Texas Tech University Health Sciences Center (TTUHSC) to examine how alternative polyadenylation (APA) of mRNAs contributes to the development and progression of Alzheimer's disease (AD). The project has two main goals: 1) to identify APA genes and pathways associated with AD pathology using computational analysis of existing single-cell RNA-sequencing datasets, and 2)...
- This federal Project Grant award of $679,182, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports the development of new computational models that leverage multimodal neuroimaging and demographic data to predict post-stroke aphasia and language recovery. The key objective is to build an interpretable, modular platform that can identify effective treatments and...
- The Project Grant award, titled "Exercising Language: Behavioral and Neurophysiological Changes After High-Intensity Exercise Training in Post-Stroke Aphasia", is funded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The $702,315 award, effective May 15, 2025 through April 30, 2030, will support a study evaluating the effects of high-intensity physical exercise...
- This federal Project Grant award of $4,591,694.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to develop and validate an Alzheimer's disease-specific speech profile using automated speech analysis. The objective is to improve early detection and monitoring of Alzheimer's disease by leveraging existing and newly collected longitudinal speech samples from culturally and educationally diverse populations. The project will use machine learning algorithms to identify...
- This Project Grant award of $108,512 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders grant program (CFDA 93.173). The grant supports research to understand how the brain's anatomical network structure and connectivity influence language production and recovery in individuals with post-stroke aphasia. The research utilizes Network Control Theory (NCT) to model brain regions...
- The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $147,486 Project Grant under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program to the University of Pittsburgh. The project aims to apply principles of the Complementary Learning Systems (CLS) neurobiological framework to evaluate how sleep-related consolidation influences neural and behavioral response to aphasia treatment. Specific research objectives include exploring the...
- The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $425,814 Project Grant under the "Research Related to Deafness and Communication Disorders" (CFDA 93.173) program to Northeastern University. The grant is for a 2-year project from August 1, 2025 to July 31, 2027 to establish the preliminary efficacy of a smartwatch-based ecological momentary intervention (EMI) for improving word retrieval in post-stroke aphasia patients. The EMI will deliver...
- The University of Texas at Austin was awarded a $438,625 Project Grant from the National Institute on Aging (CFDA 93.866 Aging Research program) to conduct research on "DECODING THE HETEROGENEITY OF INTERNEURON VULNERABILITY IN AGING AND ALZHEIMER'S DISEASE: AN ULTRAPLEX CLEM APPROACH." The project aims to better understand how different subtypes of inhibitory interneurons in the hippocampus are impacted by aging and Alzheimer's disease, and how some interneurons may be more...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $5,343,452 to the University of Texas at Austin to investigate the benefits of remotely-supervised neuromodulation in treating the logopenic variant of primary progressive aphasia (LVPPA). The project aims to enhance the effectiveness of proven language treatment for LVPPA, which is characterized by a gradual decline in language abilities typically caused by Alzheimer's disease pathology, by pairing it with tailored and accessible home-based neuromodulatory intervention targeting critical brain networks. This research seeks to leverage spared brain areas to improve communication function and quality of life for individuals with LVPPA, an underrepresented population in treatment research. The award has an ultimate completion date of August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $850.2k | 9/15/25 | ||
| Not listed | $4.5m | 9/8/25 |