Project Grant R21AG098364
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $126,684 Project Grant to the University of California, Los Angeles on March 18, 2026, under the Aging Research program (CFDA 93.866) for a project period extending through September 25, 2027. This award supports basic scientific research aimed at understanding the signaling mechanisms by which estrogen influences metabolic pathways during menopause. The research focuses on elucidating how circulating estrogen affects...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $433,125 to the University of California, Los Angeles (UCLA), effective August 1, 2025, through July 31, 2027, under the Aging Research program (CFDA 93.866). This award funds a two-year research project investigating the molecular and cellular characteristics of striatal astrocytes during the aging process. The research aims to elucidate how astrocytes—a critical glial cell type involved in...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Columbia University's Health Sciences Division a $3.45 million Project Grant under the Aging Research program (CFDA 93.866) for a four-year period from September 1, 2025, through August 31, 2029. This award supports research investigating the molecular mechanisms and genetic basis of human ovarian aging in response to Notice NOT-OD-24-079 on women's health research. The project will deliver comprehensive scientific...
- Federal Project Grant Award Summary The University of California, Santa Barbara received a $4.77 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) awarded August 5, 2025, with a completion date of July 31, 2029. This award supports a multi-principal investigator research initiative investigating the effects of endocrine aging on spatial navigation ability and associated neuronal systems. The research team, composed of experts in...
- Federal Grant Award Summary The National Institute on Aging awarded a $2.22 million Project Grant to the University of California, Irvine under the Aging Research program (CFDA 93.866) for the period September 1, 2025 through August 31, 2027. This award supports the development and optimization of enhancer adeno-associated virus (AAV) vectors—genetically engineered viral tools designed to provide cell-type-specific genetic access and manipulation capabilities in the brain. The primary...
- Federal Project Grant Award Summary The University of Washington received a $651,175 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 1, 2026, with completion targeted for November 30, 2030. This award supports a longitudinal study examining the developmental pathways linking female pubertal timing to long-term cardiometabolic health outcomes and biological aging. The research utilizes participants from the National...
- Federal Project Grant Award Summary The National Institute on Aging awarded the University of Virginia a $522,167 Project Grant, effective August 1, 2025, through May 31, 2030, under the Aging Research program (CFDA 93.866). The award supports research investigating mechanisms of ribosomal DNA (rDNA) instability during aging, with the objective of understanding how genomic instability contributes to the aging process. The research focuses on characterizing the roles of the FOB1 protein and...
- Federal Project Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded a $393,750 Project Grant to the University of California, Los Angeles (UCLA) on September 22, 2025, with a completion date of August 31, 2027. This award supports a prospective cohort study investigating the impact of gastroesophageal cancer (GEC) treatments on physical function decline in older adults aged 60 years and above. The study will deliver comprehensive...
- Federal Grant Award Summary The Buck Institute for Research on Aging received $809,486 in Project Grant funding from the National Institute on Aging (CFDA 93.866 – Aging Research program) beginning February 1, 2026, through January 31, 2031. The award supports comprehensive biomedical research investigating the role of oxidation resistance 1 (OXR1) and retromer proteins in brain aging and Alzheimer's disease and related dementias (ADRD). The research leverages multiple model systems, including...
- Federal Grant Award Summary The National Institute on Aging awarded University of California, Irvine a $773,816 Project Grant under the Aging Research program (CFDA 93.866) on June 1, 2025, with a completion date of March 31, 2030. This award funds a multi-investigator research initiative investigating cell-type-specific and spatial proteogenomics analysis of aberrant RNA splicing and misfolded proteins in Alzheimer's-related tauopathies. The research team will generate single-cell spatial...
The National Institute on Aging awarded $433,125 to the University of California, Los Angeles under the Aging Research program (CFDA 93.866) on February 1, 2026, with a completion date of January 31, 2028. This project grant supports fundamental research to identify and characterize mechanisms underlying ovarian aging in mammals by leveraging bat species as novel biological models. The primary deliverable is the establishment of select bat species as validated models for ovarian aging in long-lived mammals through application of newly developed methylation-based age estimation techniques. Researchers will interrogate eight previously identified bat species to determine which ones meet established criteria for adoption as long-lived mammalian models, including demonstrating minimal ovarian aging over their extended lifespans. The research outcomes generated through this funding are intended to inform the development of bat-informed strategies to extend ovarian health-span in women, addressing a significant gap in understanding reproductive longevity and mitigating age-related fertility decline and menopause. The project directly supports the National Institute on Aging's mission to advance scientific understanding of the aging process and age-related diseases through biomedical research, with particular application to women's health and reproductive aging.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $433.1k | 1/21/26 |