Project Grant R21AG098256
- The National Institute on Aging, part of the Department of Health and Human Services, awarded New York University $3.55 million on July 15, 2026, under the Aging Research program (CFDA 93.866) to investigate the curse of choice—the phenomenon that decision quality declines as the number of available options increases, particularly in older adults with cognitive decline. The recipient will conduct research demonstrating the hyperbolic relationship between choice efficiency and choice set size;...
- The National Institute on Aging awarded the University of Pennsylvania $811,172 on September 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a five-year prospective observational study testing whether economic scarcity affects medication adherence and uptake of preventive services among older adults with chronic disease. The research enrolls 400 adults aged 50 years or older who receive Supplemental Nutrition Assistance Program (SNAP) benefits and are prescribed once-daily...
- The National Institute on Aging awarded The University of Texas Southwestern Medical Center $127,493 on August 1, 2026, under the Aging Research program (CFDA 93.866) to investigate associations between midlife hypertension and brain structure and function changes, and to assess the impact of high-intensity interval training on brain outcomes in middle-aged adults with elevated blood pressure. The project combines retrospective longitudinal analysis with a proof-of-concept randomized...
- The National Institute on Aging, a component of the Department of Health and Human Services National Institutes of Health, awarded the University of Wisconsin System Office of Sponsored Programs (operating as University of Wisconsin–Milwaukee) $642,805 under the Aging Research program (CFDA 93.866) on January 15, 2026. The award funds three experiments investigating how older age affects memory integration—the ability to generalize across experiences, make inferences, and accumulate knowledge....
- The National Institute on Aging, part of the Department of Health and Human Services, awarded The University of Texas Southwestern Medical Center $249,000 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop and validate an innovative genetic platform for de-risking g-secretase modulator therapeutics in Alzheimer's disease. The award funds two primary aims. Aim 1 involves using CRISPR/Cas9 engineering and structure-informed design to generate and validate a novel...
- The National Institute on Aging awarded the University of Texas at Austin $650,447 on September 1, 2026, under the Aging Research program (CFDA 93.866) to develop a profile-based framework for matching transitional care services to distinct patient-caregiver groups among persons living with dementia (PLWDs). The award funds research to identify patient-caregiver profiles and co-develop provider and system implementation tools that enable tailored, evidence-based transitional care delivery across...
- The National Institute on Aging awarded The University of Texas Southwestern Medical Center $799,870 on September 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a randomized controlled trial testing a multi-dimensional tailored telehealth intervention for heart failure with preserved ejection fraction in older adults. The intervention integrates physical rehabilitation targeting strength, balance, mobility, and endurance with health coaching addressing emotional regulation...
- The National Institute on Aging awarded Texas A&M University $640,059 on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate cerebellar changes in aging and cognitive decline through longitudinal neuroimaging and functional analysis. The project examines how cerebellar structure, white matter circuits, and task-based functional activation change over time in older adults, with particular focus on individuals experiencing subjective cognitive decline—self-reported...
- The National Institute on Aging awarded New York University $6.203 million on September 15, 2025, under the Aging Research program (CFDA 93.866) to examine peripheral immune markers and vascular dysfunction as contributors to cognitive decline and Alzheimer's disease. The research integrates circulating biomarkers—platelet aggregation, neutrophil activity, and proteomic data—with advanced imaging to assess associations between vascular and immune dysfunction and cerebrovascular burden, amyloid...
- The National Institute on Aging awarded the University of California Irvine $5,101,916 on July 1, 2026, under the Aging Research program (CFDA 93.866) to examine daily dynamics of social connection and their influence on physical and cognitive functioning across the adult lifespan. The research uses longitudinal daily diary datasets from the Midlife in the United States Study (MIDUS), including four waves of diary data across approximately 20 years (beginning in 2002, 2014, and 2023) and two...
The National Institute on Aging, part of the Department of Health and Human Services, awarded $437,250 to the University of Texas at Dallas on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate affective forecasting as a strategy for reducing temporal discounting across adulthood. The research addresses a critical gap in interventions for temporal discounting—the tendency to devalue delayed rewards in favor of immediate ones—which has serious implications for health behavior and outcomes. Existing interventions have proven unsuccessful in healthy older adults and those with neurodegenerative disorders like Alzheimer's disease. The project hypothesizes that engaging in affective forecasting during decision-making, which relies on psychological and brain mechanisms preserved in older age, may effectively reduce temporal discounting, particularly in older adults. The recipient will pursue two specific aims across two studies with participants aged 25–85 recruited to create samples equally distributed across the lifespan. In Study 1, 200 online participants will complete an intertemporal choice task selecting between smaller, sooner and larger, later monetary rewards, then predict how they would feel receiving the delayed rewards. Three rewards will be realized after the stated time delay, with participants providing real-time feeling ratings upon receipt via smartphone. Study 2 will determine whether directed affective forecasting reduces temporal discounting across adulthood. Performance occurs in Richardson, Texas. The award period runs from September 1, 2026, through August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $437.3k | 8/31/26 |