Project Grant R21AG093628
- Summary of Federal Project Grant Award Cornell University's Office of Sponsored Programs received a $2.21 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded August 15, 2025, with completion scheduled for July 31, 2029. This research initiative, performed at Cornell's Ithaca, New York location, delivers comprehensive scientific research and analysis directed toward understanding the mechanisms of cellular aging and autophagy....
- Federal Project Grant Award Summary The National Institute on Aging awarded a $423,750 Project Grant to Weill Medical College of Cornell University on August 15, 2025, under the Aging Research program (CFDA 93.866). This research project, scheduled for completion by July 31, 2027, will investigate the impact of biological age on surgical outcomes in older adults. The primary deliverables include scientific research to determine the effect of preoperative biological age on one-year...
- Federal Project Grant Award Summary Weill Medical College of Cornell University received a $466,125 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded August 1, 2025, with completion scheduled for July 31, 2027. This award funds a two-year research initiative investigating hepatic aging mechanisms and alcohol-associated liver disease (ALD) in elderly populations. The project delivers scientific research services focused on...
- Federal Project Grant Award Summary The University of Pennsylvania received a $2.8 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective February 1, 2026 through January 31, 2031. This award supports a continuation of a prior Program Project Grant (PPG) focused on epigenetics of aging and age-associated diseases. The research investigates two primary areas: chromostasis (homeostatic mechanisms that maintain dynamic chromatin...
- Federal Project Grant Award Summary The University of Michigan, through its Office of Research and Sponsored Projects, received a $2,991,725 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) effective September 1, 2025, with a completion date of August 31, 2029. This award funds a comprehensive research initiative investigating reactive oxygen species (ROS) as modulators of lifespan and aging processes. The research examines how early-life...
- Federal Grant Award Summary This Project Grant award of $109,076, issued on March 3, 2026, by the National Institute on Aging under the Aging Research program (CFDA 93.866), supports research investigating vulnerable cell populations in aging-induced circadian clock remodeling and disruption through March 2029. The primary deliverable is a comprehensive scientific investigation utilizing high-throughput single-nucleus RNA sequencing (snRNA-seq) of flash-frozen tissue samples to identify key cell...
- Federal Grant Award Summary The National Institute on Aging awarded $148,614 to Weill Medical College of Cornell University on March 17, 2026, under the Aging Research program (CFDA 93.866) to support research on lysosome homeostasis in aging-related diseases through September 21, 2027. This Project Grant funds scientific investigation aimed at understanding how cells sense and respond to lysosomal stress through the regulation of lysosome turnover and biogenesis mechanisms. The research...
- Federal Project Grant Award Summary The University of Rochester received a $656,829 Project Grant award from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective January 1, 2026 through December 31, 2030. This research initiative investigates the selective vulnerability of the fronto-insular network (FIN)—comprising the medial prefrontal cortex and anterior insular cortex—in aging and Alzheimer's disease (AD). The project integrates in vivo structural,...
- Federal Project Grant Award Summary Weill Medical College of Cornell University received a $711,898 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 30, 2025, with a completion date of June 30, 2030. The award supports biomedical research directed toward understanding the mechanisms by which apolipoprotein E4 (E4), the predominant genetic risk factor for Alzheimer's disease, contributes to tau-induced...
- Federal Grant Award Summary The University of Rochester received a $924,002 Project Grant award from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective July 1, 2025, through May 31, 2030. The award establishes the Upstate New York Nathan Shock Center of Excellence in Basic Biology of Aging (UPSTATE NSC), a collaborative research resource center between the University of Rochester and Cornell University focused on comparative biology of aging. The center...
Cornell University received a $458,871 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) to conduct research on epigenetic aging in laboratory mice. The award, effective February 1, 2026 through January 31, 2028, supports an innovative experimental paradigm that studies mice in semi-natural outdoor enclosures—a "rewilding" approach designed to bridge ecological and biomedical research methodologies. This research addresses a critical gap in aging science by examining how natural complexity in physical and social environments influences epigenetic aging patterns and behavioral senescence, moving beyond the limitations of traditional laboratory settings that may obscure important environmental influences on age-related biological changes. The funded research will compare genome-wide methylation patterns and behavioral performance between age-matched laboratory mice raised in conventional laboratory environments and those maintained in field enclosures. Building on preliminary data indicating accelerated epigenetic aging in liver tissue among rewilded mice, the study will determine whether similar patterns extend to other tissues, behavioral measures, and overall lifespan. The research will be conducted at Cornell University's Ithaca, New York campus through the Office of Sponsored Programs, generating empirical evidence on how environmental realism shapes aging biology in a mammalian model organism.Federal Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $458.9k | 1/27/26 |