Project Grant R03AG095722
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $699,344 to Albert Einstein College of Medicine to investigate the impact of surgical stress on age-related changes and resilience, with a focus on sex differences. The project aims to quantify the spatial, temporal, and sex-dependent effects of surgical stress on aging hallmarks and determine how resilience may modulate these relationships. The 2-year award period runs from September 1, 2025 to...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $159,492 to Weill Medical College of Cornell University to support research focused on identifying and characterizing clonal expansions in aging and aging-related diseases. The key products/services to be delivered under this award include: Developing tools to enable the identification of candidate somatic variants at scale from publicly available data using machine learning approaches. Applying...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,208,503.00 to Cornell University to conduct research on the role of autophagy in cellular aging. The project, titled "System-wide and Mechanistic Deconvolution of Autophagy in Cellular Aging", aims to systematically investigate how different forms of autophagy influence cellular aging processes, with a focus on understanding how modulating selective autophagy pathways such...
- This $2,356,117 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will support research to improve the perioperative management of patients with Alzheimer's disease and related dementias. The primary objectives are to: (1) identify the extent to which surgical patients with these conditions are at increased risk for adverse postoperative outcomes, and (2) estimate the association between various perioperative interventions and the incidence...
- This federal Project Grant award of $291,913 was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to Virscio, Inc., a for-profit research company located in Connecticut. The award is focused on developing epigenetic and senescent biomarkers using non-human primate tissues to advance the understanding of biological aging processes and potential anti-aging strategies. The project aims to create minimally invasive biomarker tools, such as blood and skin-based assays,...
- This federal Project Grant award of $3,445,585 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research to investigate the molecular mechanisms and genetic factors underlying human ovarian aging. The research aims to advance scientific understanding of how ovarian aging proceeds and its connections to broader women's health outcomes. The award recipient, The Trustees of Columbia University in the City of New York, will utilize single-cell sequencing techniques to...
- The University of Pittsburgh received a $801,268 Project Grant award from the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866). The objective of this 5-year award, with a start date of June 1, 2025, is to develop an effective evidence-based approach to providing value-based perioperative care in high-risk elderly surgical patients. The project aims to improve prediction and prevention of postoperative mortality, delirium, cognitive decline, and other...
- The National Institute on Aging (NIA) awarded a $805,295 Project Grant under the Aging Research federal grant program (CFDA 93.866) to The Leland Stanford Junior University, effective April 1, 2025 through March 31, 2030. The purpose of this grant is to examine cerebrospinal fluid (CSF) and blood biomarkers to gain insights into the pathways leading to postoperative delirium and neurocognitive dysfunction, which commonly occur after surgical procedures and are associated with declines in...
- This Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) is supporting the development of a "Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer's Disease and Longevity". The $802,034 award aims to conduct multi-modal analyses of genetics, multi-omics data, cross-species protein interactome networks, and human brain-specific functional genomic data to identify...
- This federal Project Grant award of $240,069 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Vanderbilt University will be used to explore the effects of lifestyle on immune system activity and molecular markers of aging across populations with diverse lifestyles, from traditional subsistence-level to highly urban. The research will focus on analyzing three age-associated molecular phenotypes - gene expression, DNA methylation, and telomere length - in peripheral blood...
This Project Grant award, funded by the National Institute on Aging (CFDA 93.866 Aging Research), aims to determine the impact of biological age on surgical outcomes among older adults. The $423,750 award, with a period of performance from August 15, 2025 to July 31, 2027, will be used by Weill Medical College of Cornell University to: (1) Evaluate the effect of preoperative biological age, as measured by immunologic and metabolic markers, on 1-year post-operative mortality; and (2) Assess preoperative biological age as a predictor of loss of independence following surgery. This research project will leverage the large, integrated dataset of the UK Biobank to investigate how biological age, rather than just chronological age, impacts surgical risks and recovery in the growing older adult population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $423.8k | 8/7/25 |