Project Grant R21AG093093
- Federal Grant Award Summary The National Institute on Aging awarded a $666,504 Project Grant to the University of Kentucky Research Foundation on February 1, 2026, under the Aging Research program (CFDA 93.866). This five-year research initiative, extending through January 31, 2031, focuses on developing and validating noninvasive magnetic resonance imaging (MRI) biomarkers to assess muscle quality in older adults with knee osteoarthritis. The project will evaluate advanced MRI techniques,...
- Federal Project Grant Summary Award Details: New York University School of Medicine received a $708,137 project grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective February 1, 2026, through January 31, 2030. Products and Services: The award supports development and validation of genetically encoded multimeric particles (GEMs)—self-assembling probe particles designed to advance microrheology research on cellular biophysical properties...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $242,846 Project Grant to the Icahn School of Medicine at Mount Sinai on August 15, 2025, under the Aging Research program (CFDA 93.866). The grant funds the development and validation of a novel chest computed tomography (CT)-based frailty screening tool utilizing artificial intelligence (AI)-assisted multi-organ body composition analysis. The five-year project, scheduled for completion by July 31, 2030,...
- Federal Grant Award Summary New York University School of Medicine received a $642,063 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective January 15, 2026, with completion targeted for December 31, 2030. The award supports a collaborative research investigation examining gabaergic microcircuits in the hippocampal CA1 region to identify cellular targets and neuromodulatory mechanisms for early-stage Alzheimer's disease (AD)...
- Federal Grant Award Summary New York University received a $1,012,879 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded September 5, 2025, with completion anticipated by August 31, 2029. The award supports the development of three novel statistical machine learning methods designed to enhance the understanding, diagnosis, and prediction of Alzheimer's disease using multi-view data integration. The primary deliverables include: (1) a...
- Federal Grant Award Summary New York University was awarded $1,049,816 through the National Institute on Aging's Aging Research program (CFDA 93.866) effective May 15, 2025, with a completion date of January 31, 2029. This project grant supports the development of statistical methodologies to improve the estimation and prediction of Alzheimer's disease (AD) progression using longitudinal cohort study data. The research addresses critical gaps in current analytical approaches by developing...
- Federal Project Grant Award Summary New York University School of Medicine received a $705,726 project grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective September 1, 2025 through August 31, 2028. The award funds a multi-center feasibility randomized clinical trial examining Monitored Anesthesia Care with Soft-Tissue Infiltration with Local Anesthesia (MAC-STILA) as an alternative anesthetic approach for older adults undergoing hip fracture...
- Federal Project Grant Award Summary The National Institute on Aging awarded $698,690 to the University of Wisconsin-Madison under its Aging Research program (CFDA 93.866) effective February 1, 2026, through January 31, 2031. This Project Grant supports basic research investigating the molecular mechanisms underlying fiber type-specific skeletal muscle dysfunction in aging populations. The research project will deliver scientific findings and data products examining how aging affects slow...
- Federal Grant Award Summary Panorama Research Incorporated received a $354,000 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), with an award date of September 20, 2025, and completion date of September 19, 2026. The company will develop novel therapeutic formulations of Isthmin 1 (ISM1), an adipokine designed to address sarcopenia—age-related loss of skeletal muscle mass, strength, and quality. The research will generate...
- Federal Grant Award Summary The National Institute on Aging awarded a $116,710 Project Grant to the University of Connecticut, Office Sponsored Programs, effective August 1, 2025 through April 30, 2030, under the Aging Research program (CFDA 93.866). This career development award supports research to establish sex-specific determinants of muscle quality in older adults, with particular focus on understanding how males and females experience different mechanisms of sarcopenia—the age-related loss...
New York University School of Medicine received a $466,125 Project Grant award from the National Institute on Aging (Aging Research program, CFDA 93.866) effective January 15, 2026, with completion targeted for December 31, 2027. The award supports development of innovative magnetic resonance imaging (MRI) analysis tools and frameworks designed to identify microstructural and structural biomarkers of skeletal muscle health across the lifespan. The research specifically addresses the clinical challenge of early detection and monitoring of sarcopenia, an age-related condition responsible for significant disability, mortality, and estimated annual healthcare costs of $18 billion in the United States. The primary deliverables include: (1) analytical tools utilizing muscle shape and structural information to predict muscle strength and facilitate retrospective analysis and opportunistic screening of sarcopenia; and (2) a novel diffusion MRI framework with enhanced sensitivity and specificity for detecting cellular atrophy at earlier disease stages. These quantitative MRI tools are designed to investigate muscle quality and structure in correlation with patient strength and functional status, thereby enabling non-invasive, earlier detection of sarcopenia when intervention strategies are more likely to be effective. The research outcomes will support improved clinical management and diagnostic capabilities for age-related muscle deterioration.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $466.1k | 1/9/26 |