Project Grant K76AG095108
- This $789,664 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a research project titled "Dissecting the Cellular and Spatial Tissue Clock of the Human Lung and Peripheral Blood" at the Icahn School of Medicine at Mount Sinai. The project aims to leverage single-cell RNA sequencing and spatial transcriptomics to characterize the effect of age on the cellular microenvironment of the human lung and peripheral blood. The research will...
- This $422,500 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the Icahn School of Medicine at Mount Sinai (ISMMS) will support research to examine the drivers of high out-of-pocket spending and burdensome care for older adults with serious illness. The study aims to better understand how insurance generosity affects out-of-pocket spending and care experiences for this population, particularly at the onset of serious illness. The research project will...
- This federal Project Grant award of $145,566 from the National Institute on Aging (CFDA 93.866 - Aging Research) is supporting research at the Icahn School of Medicine at Mount Sinai to investigate how the brain accumulates and utilizes "cognitive maps" - internal neural representations that enable flexible behavior and memory recall. The research aims to provide insights into the neuronal coding deficits underlying cognitive decline, with the goal of informing therapeutic...
- This $463,625 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) supports research to better understand the effects of aging on the lung adenocarcinoma (LUAD) tumor microenvironment. The Icahn School of Medicine at Mount Sinai will use single-cell RNA sequencing and spatial analysis technologies to characterize age-related cellular and molecular changes in the LUAD tumor microenvironment. This research aims to uncover new therapeutic opportunities to modulate...
- The National Institute on Aging (NIA) awarded a $333,125 Project Grant under the Aging Research (CFDA 93.866) federal grant program to George Washington University. The grant, which runs from September 17, 2024 to August 31, 2025, will fund the development and validation of artificial intelligence algorithms to predict body composition and physical function in older adults using low-cost 3D optical body scanning technology. The research aims to provide accessible and scalable methods to assess...
- This Project Grant award of $1,526,628.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research by Cedars-Sinai Medical Center to develop Artificial Intelligence (AI) methods for analyzing echocardiography data to predict biological cardiovascular age and identify trajectories of accelerated versus delayed cardiovascular aging. The research aims to capture an aggregate measure of cardiac aging and identify potential interventions to...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $245,434 to Wake Forest University Health Sciences to conduct research on preserving muscle and bone health in older adults undergoing weight loss interventions. The 2.5-year project aims to develop automated analysis techniques to measure changes in muscle quantity and quality, as well as bone strength, using computed tomography (CT) scans collected as part of an ongoing clinical trial....
- This $6,925,230 Project Grant award from the National Institutes of Health (NIH) National Institute on Aging (CFDA 93.866 - Aging Research) will support a research project at The Trustees of Columbia University in the City of New York to develop a "Multi-Organ Chart of Personalized Susceptibility to Alzheimer's Disease and Aging." The overarching goal is to use large-scale multi-omics, multi-organ biomedical data, advanced artificial intelligence/machine learning, and computational...
- This federal Project Grant award, titled "BEFITME II: Applying User-Centered Co-Design and Implementation Science to Enhance Prehabilitation for Frail Older Adults Undergoing Lung Cancer Surgery", is funded by the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $243,000. The award, with an ultimate completion date of May 31, 2030, aims to develop and evaluate a wearable technology-based prehabilitation application that provides and tracks self-guided,...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $159,492 to Weill Medical College of Cornell University to support research focused on identifying and characterizing clonal expansions in aging and aging-related diseases. The key products/services to be delivered under this award include: Developing tools to enable the identification of candidate somatic variants at scale from publicly available data using machine learning approaches. Applying...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $242,846.00 to the Icahn School of Medicine at Mount Sinai to develop and validate a novel chest CT-based frailty screening tool using artificial intelligence. The goal is to enable opportunistic frailty assessment during routine cardiac imaging procedures in older adults with stable ischemic heart disease, addressing the limited adoption of frailty screening in clinical practice. The project will leverage existing chest CT data from cardiovascular imaging studies to create an AI-assisted multi-organ body composition analysis system for early detection of frailty, with the potential to guide personalized treatment decisions and improve outcomes for this high-risk patient population. This innovative application of existing imaging data is expected to be completed by July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $242.8k | 8/11/25 |