Project Grant R21AG086646
- Federal Project Grant Award Summary The University of Delaware received a $601,120 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), awarded on September 24, 2025, with a completion date of August 31, 2030. This translational validation study will develop and deploy next-generation diagnostic methods for assessing bone fracture healing using ultrashort echo...
- Federal Grant Award Summary The University of Pennsylvania received a $109,076 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective November 27, 2025, with completion expected by May 31, 2030. This award funds research investigating the modulation of synovial mechanobiology to mitigate disease progression in osteoarthritis (OA), a condition affecting nearly 8% of the global population with particular burden among older adults. The...
- Summary of Federal Project Grant Award The University of Delaware received a $350,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 4, 2025, with a completion date of May 31, 2030. This award supports fundamental research to examine cellular heterogeneity and niche regulation in temporomandibular joint (TMJ) osteoarthritis, a degenerative joint disease affecting...
- Federal Grant Award Summary The University of Delaware received a $436,658 Project Grant from the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded on August 7, 2025, with a completion date of July 31, 2027. This award supports research directed at establishing a stable, integrated production cell line for recombinant Adeno-Associated Virus (rAAV) through...
- Federal Grant Award Summary The University of Delaware received a $500,000 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), effective September 30, 2025, with an ultimate completion date of September 29, 2027. This award supports the validation and implementation of an upper extremity vascular contracture-specific health-related quality of life battery. The project will develop and establish standardized measurement...
- Federal Grant Award Summary Rowan University received a $530,469 Project Grant award from the National Institute on Aging under the Aging Research program (CFDA 93.866) on August 15, 2025, with a completion date of July 31, 2028. The research investigates the role of orosomucoid1 (a protein) in mitigating sarcopenia—age-related loss of muscle mass and function—during combined pharmacological and exercise interventions. The project delivers scientific research examining molecular mechanisms by...
- Federal Project Grant Award Summary The University of Delaware received a $2.61 million Project Grant award from the National Institute on Aging under the Aging Research program (CFDA 93.866), effective September 1, 2025, through August 31, 2029. This research initiative will produce evidence-based findings on the safety and effectiveness of different hypertension treatment strategies for older adults with Alzheimer's disease and related dementias (ADRD) residing in nursing homes. The project...
- Federal Project Grant Award Summary Old Dominion University Research Foundation (Odurf) received a $154,969 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 20, 2025, with completion targeted for June 30, 2029. The award funds a longitudinal research study examining the independent and interactive effects of chronic ankle instability (CAI) and aging on joint health,...
- Federal Project Grant Award Summary The University of Delaware received a $651,816 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) to investigate cardiovascular sympathetic nervous system dysfunction during the menopausal transition. The award, effective February 1, 2026 through January 31, 2031, will fund a comprehensive research study examining how physiological changes in follicle-stimulating hormone (FSH) and estradiol (E2) during...
- Grant Award Summary The University of Delaware received a $167,000 Project Grant from the National Science Foundation's Division of Computer and Network Systems under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), effective August 1, 2025 through July 31, 2029. This collaborative research project will develop an advanced multi-level control architecture for powered lower limb prostheses designed to enhance mobility over challenging and uneven terrains. The...
The University of Delaware received a $560,380 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded on January 15, 2026, with completion targeted for December 31, 2028. The project delivers novel biomechanical assessment capabilities for osteoarthritis research through the application of a force-sensing universal robotic testing system to characterize multi-axial joint function in mouse models. The system will quantify immediate and progressive biomechanical effects of two common orthopaedic injury models—medial meniscus destabilization and anterior cruciate ligament rupture—by measuring changes in relative knee motion under clinically relevant translational and rotational loading paradigms that mirror standard clinical orthopaedic assessments. The research products will provide comparative functional and structural outcome data across multiple mouse trauma models, enabling more informed model selection for future osteoarthritis studies. By establishing direct comparison points between rodent injury models and published human subject data, the project advances pre-clinical research methodology and facilitates translation of findings into clinically meaningful insights regarding disease progression and functional consequences of joint injuries in aging populations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $560.4k | 1/9/26 |