Project Grant R21AG081704

Award Date 8/15/24
Completion Date 7/31/26
Dollars Obligated $236K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Atlanta, GA 30332, USA
Similar Awards
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the Lovelace Biomedical Research Institute aims to investigate the mechanisms by which transcranial alternating current stimulation (tACS) and transcranial direct current stimulation (tDCS) modulate cerebral microvascular function and its influence on neuronal activity. The $1,193,500 award will support in-vivo awake multiphoton laser scanning microscopy studies to assess cerebral microvascular...
This federal Cooperative Agreement award, provided by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to investigate the mechanisms and optimize the efficacy of paired vagus nerve stimulation (VNS) in improving upper extremity motor function for patients with chronic stroke. The $1,038,313 award, with a performance period from September 2024 to August 2029, will support research to...
This five-year, $147,933 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a study to investigate the effects of transcranial direct current stimulation (tDCS) on working memory performance and functional connectivity in individuals with mild cognitive impairment (MCI). The overarching research goal is to characterize the impact of acute, fixed-dose tDCS application on working memory and brain networks in the MCI population compared to healthy...
The National Institute on Aging (NIA) awarded a $835,056 Project Grant (CFDA 93.866 - Aging Research) to Trustees of Tufts College (Tufts University) to develop a multi-modal system of wearable biosensors and machine learning algorithms for the continuous monitoring of mobility and cognitive function in older adults. The project aims to advance personalized health sensing and informatics to enable early detection and prediction of Alzheimer's disease and related dementias (AD/ADRD). Key...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $640,000 in funding to Northeastern University to develop and apply new intravital microscopy techniques. The goal is to gain greater insight into the effects of gamma entrainment, a non-pharmacological neuromodulation technique, on cerebral energy metabolism and microvascular hemodynamics in Alzheimer's disease (AD) models. The project will nondisruptively characterize cellular-level changes to...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to Brandeis University will conduct research to understand the neurobiological mechanisms underlying daily life activity participation in older adults and its relationship to Alzheimer's disease pathology. The $148,568 award, running from November 2024 to January 2026, will employ a multilevel, multimodal approach using behavioral, psychophysiological, neuroimaging, and naturalistic methods. Key...
This Project Grant award from the National Institute on Aging (Federal Grant Program CFDA 93.866 - Aging Research) totaling $698,870.00 will support research to investigate the effects of thalamic stimulation on sleep oscillations in humans. The key products and services to be delivered under this award include: Studying the spatial extent of thalamic stimulation-evoked spindles and the disruption of spindles through real-time closed-loop stimulation in 50 patients with medication-refractory...
The National Institute on Aging (NIA) awarded a $227,740 Project Grant (CFDA 93.866 - Aging Research) to the University of Florida to investigate the effects of transcutaneous spinal direct current stimulation (tsDCS) as an adjunct therapy to dynamic balance training in older adults with balance and walking deficits. The study aims to assess whether active tsDCS combined with balance training can enhance practice-related gains and retention in balance and walking performance, and whether this is...
This Project Grant from the National Institutes of Health's National Institute on Aging, under the Aging Research program (CFDA 93.866), provides $287,218.16 in funding to the University of Maryland, Baltimore from August 1, 2021 through March 27, 2022. The award supports research aimed at better understanding the impact of aging on muscle excitability and action potential conduction velocity. Specifically, the recipient will use electrophysiology techniques and optical imaging to examine...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $440,610 to Yale University to conduct research on motor learning and adaptation. The project aims to investigate the neural signals and processes underlying motor learning in upper-limb movements and speech, with a focus on understanding how motor planning and prediction...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will explore the efficacy of applying transcutaneous vagus nerve stimulation (TVNS) during motor skill training to enhance motor learning in healthy older adults. The primary goal is to examine the effect of post-success TVNS during motor training on motor learning outcomes in this population. The project will also investigate whether the motor learning facilitation is associated with acute neuromodulation responsiveness to TVNS. Awarded to the Georgia Tech Research Corporation, the project will receive $236,094 in funding from Aug 2024 to Jul 2026. The findings could have clinical significance for treating movement disorders associated with neurological conditions and healthy aging.

Generated 7/1/25, 2:21 AM