Project Grant R21AA031130
- The National Institute on Alcohol Abuse and Alcoholism awarded Texas A&M University System Health Science Center $635,002 on June 15, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate cholinergic modulation of striatal circuits in alcohol use disorder. The project examines how chronic alcohol intake affects acetylcholine signaling in the dorsomedial striatum, focusing on the interaction between direct-pathway medium spiny neurons and cholinergic interneurons. Research...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Wisconsin–Milwaukee $413,383 on July 16, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct a meta-analytic structural equation modeling study examining mechanisms of parenting on adolescent alcohol use. The recipient will conduct a systematic review and meta-analysis of empirical studies targeting U.S. adolescents aged 10 to 18, synthesizing evidence on the influence of alcohol-specific parenting...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Texas at Arlington $720,437 on May 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct a hybrid Type 1 effectiveness-implementation trial evaluating parent-based interventions for adolescent alcohol prevention that incorporate social media content and personalized feedback. The research addresses the gap between evidence that alcohol parent-based interventions reduce adolescent drinking and the...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $167,500 in Project Grant funding to the University of Massachusetts Medical School on September 17, 2025, through the Alcohol Research Programs (CFDA 93.273) for a research study investigating sex differences in excessive alcohol use patterns across young adulthood and middle age. The research will utilize longitudinal data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) to examine how...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Texas at Austin $160,988 on March 9, 2026, under the Alcohol Research Programs (CFDA 93.273) to support a project investigating the role of the gut microbiome in alcohol use disorder using a rodent model. The research employs high drinking in the dark mice (IHDID), a genetic model for heightened alcohol consumption, to explore whether gut microbial species are altered by alcohol exposure and whether the gut...
- The National Institute on Alcohol Abuse and Alcoholism awarded The University of Texas Health Science Center at San Antonio $664,792 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate post-transcriptional mechanisms and cellular senescence in age-related alcoholic liver disease. The research targets dysregulated nutrient sensing as a hallmark of aging that drives hepatic steatosis progression toward cirrhosis and hepatocellular carcinoma. The recipient will...
- The National Institute on Alcohol Abuse and Alcoholism awarded Yale University $880,688 on August 4, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct research imaging glucocorticoid function in women with childhood trauma and alcohol use disorder. The research uses positron emission tomography with a novel radiotracer called [18F]FMOZAT to investigate brain cortisol as a potential biomarker of stress dysregulation in women with childhood trauma and alcohol use disorder. The...
- The National Institute on Alcohol Abuse and Alcoholism awarded Children's Research Institute $648,180 on June 20, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate mechanisms and potential pharmacotherapy of neurocognitive deficits in fetal alcohol spectrum disorders. The research examines the long-term neurobehavioral impact of prenatal alcohol exposure, with focus on apolipoprotein E (APOE) signaling in the motor cortex as a therapeutic target. The project builds on...
- The National Institute on Alcohol Abuse and Alcoholism awarded Research Triangle Institute $1,411,804 on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a hybrid implementation effectiveness cluster-randomized trial of Better Informed Parents Keeping Adolescents Safe from Alcohol (BIPAS), a mobile-delivered digital intervention designed to help parents prevent early-onset alcohol use in children. The study will expand BIPAS reach by translating the intervention...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Texas Health Science Center at Houston $1.772 million on September 15, 2025, under the Alcohol Research Programs (CFDA 93.273) to develop and validate a microbial-based platform for assessing alcohol-related organ damage in alcohol use disorders. The recipient will develop a comprehensive web-based knowledge module integrating microbiota, metabolites, and host pathways to map microbial signatures and mechanisms...
The National Institute on Alcohol Abuse and Alcoholism awarded Texas A&M University $237,595 on July 20, 2026, for a Project Grant (R21AA031130) under the Alcohol Research Programs (CFDA 93.273) to investigate the relationship between maternal identity, social group identification with alcohol use, and maternal drinking and parenting behaviors. The research examines whether the cultural phenomenon of the "wine mom"—which frames drinking as socially acceptable within motherhood—activates neural mechanisms that increase alcohol salience and influence maternal drinking patterns and parenting dynamics with toddlers. The study will test effects across three aims: demonstrating whether maternal-identity-linked alcohol associations increase alcohol cue salience; examining concurrent relationships between such associations and maternal drinking behaviors and parenting observations; and assessing longitudinal outcomes. Research is performed in College Station, Texas, with a period of performance extending from the award date through June 30, 2028. The assistance type is Project Grant, supporting fundamental research to develop knowledge applicable to prevention and treatment of alcoholism and alcohol-related problems.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $237.6k | 7/22/26 |