Project Grant R15GM160969
Award Date 9/1/25
Completion Date 8/31/28
Dollars Obligated $557K
Funding Federal Agency
Awarding Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
St. Louis, MO 63103, USA
Similar Awards
- This federal Project Grant award for $460,413.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a novel visible light-induced transition metal-radical hybrid catalytic methodology for regiocontrolled, mild, and exogenous oxidant-free functionalizations of saturated groups. The proposed research seeks to create a platform for controlled, selective functionalization of organic...
- The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Massachusetts Institute of Technology (MIT) for $351,010. The grant, with a period of performance from January 1, 2025 to November 30, 2029, focuses on the rational design, synthesis, and characterization of cationic carbone-boracycles as far-red and near-infrared photoactive agents for applications in bioimaging and cancer therapy....
- This federal Project Grant award of $386,617 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) aims to develop safer and more efficient chemical methods for the synthesis of complex, fluorinated, and highly functional pharmaceutical compounds. The key research areas encompass: (1) electromicellar catalysis for the formation of fluorinated heterocycles, allenes, and reactive intermediates; (2) enantioselective...
- This federal Project Grant award of $151,040.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to The Regents of the University of California, doing business as the University of California, Berkeley. The funding supports research to develop supramolecular photocatalysts that can enable novel photochemical reactions to produce oxygen- and nitrogen-containing heterocycles in a highly selective...
- The U.S. National Institute of General Medical Sciences (NIGMS) awarded a $416,625 Project Grant to Saint Louis University under the Biomedical Research and Research Training program (CFDA 93.859) to develop innovative optical tools to control endogenous G protein-coupled receptors (GPCRs) in unmodified cells and in vivo. The project aims to: (1) enable optical control of endogenous GPCRs, (2) control GPCRs and endogenous G proteins at specific subcellular locations like the Golgi and nuclear...
- The National Science Foundation awarded a $495,964 project grant to Saint Louis University under the Mathematical and Physical Sciences federal grant program (CFDA 47.049). The grant will fund research into developing a conceptual framework for the rare dual-release photochemistry of sulfoximes and sulfondiimines. Professor Ryan McCulla of Saint Louis University's Department of Chemistry will investigate the photochemistry of these compounds, which can release two different reactive...
- This $244,450 Project Grant, awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to understand the catalytic mechanisms, structural dynamics, and biomedical importance of two key classes of metalloenzymes: matrix metalloproteinases (MMPs) and iron(II)/2-oxoglutarate (2OG)-dependent oxygenases. The project, spanning July 2025 to June 2030, aims to provide missing knowledge on these...
- This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $535,000 to Case Western Reserve University to support research developing new classes of organic compounds absorbing one or two photons in the near-infrared range for applications including photodynamic therapy. Professor Carlos E. Crespo-Hernández will lead efforts to deliberately design and synthesize thionated organic photosensitizers...
- The project grant award of $1,925,000 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the structural dynamics and regulation of the mitochondrial pyruvate carrier (MPC) at Saint Louis University. The research aims to uncover the conformational changes of the MPC during pyruvate transport and inhibition using electron paramagnetic resonance (EPR) spectroscopy techniques, as...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is funding the development of new fluorescent imaging probes that can detect and map reactive oxygen and nitrogen species in living cells. The goal is to create a toolkit of probes with different optical characteristics spanning the visible spectrum, enabling multi-color imaging of these oxidative metabolites. This $540,053 award...