Project Grant R15ES038676
- The National Institute of Environmental Health Sciences awarded the University of Cincinnati $698,212 on April 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate the impact of micro- and nanoplastics on cardiac toxicity and heart disease susceptibility. The research addresses mechanisms by which micro- and nanoplastics cause cardiac damage, focusing on mitochondrial dysfunction and oxidative stress in the heart. Preliminary findings show that exposure to micro- and...
- The National Institute of Environmental Health Sciences awarded the Board of Regents of the University of Nebraska $1,479,178 on September 9, 2025, under the Environmental Health program (CFDA 93.113) to quantify the release of nano- and microplastics from plastic food containers into water and beverages and assess potential health risks. The project measures the release of nano- and microplastics from reusable plastic cups, single-use water and soft drink bottles, and takeaway coffee cups...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $152,500 on August 15, 2026, under the Environmental Health program (CFDA 93.113) to define dose-response relationships and renal functional impairment from simultaneous exposure to micro- and nano-plastics and arsenic. The research establishes a quantitative framework for how micro- and nano-plastics behave when co-present with arsenic in the body, whether their excretion is...
- The National Institute of Environmental Health Sciences awarded Morgan State University $142,399 on August 7, 2026, under the Environmental Health program (CFDA 93.113) to investigate the cardiac effects of weathered microplastics through aligned in vitro, ex vivo, and in vivo experimental systems. The research tests whether environmentally realistic weathered microplastics induce distinct and potentially more harmful biological effects on mammalian hearts than pristine microplastics....
- The National Institute of Environmental Health Sciences awarded New York University $10.907 million on September 15, 2025, under the Environmental Health program (CFDA 93.113) to conduct a translational study on the accumulation of micro- and nanoplastic particles in mammalian tissues. The research investigates inter-tissue accumulation of micro- and nanoplastic particles across the lifespan, including the quantified concentration of these particles within systemic tissues, the role of sex, age,...
- The National Institute of Environmental Health Sciences awarded $765,348 to the University of California, Davis on April 14, 2026, under the Environmental Health program (CFDA 93.113) to investigate pollutant-adsorbed nanoplastics and their health impacts following inhalation exposure. The research addresses the formation, distribution, and neurotoxic effects of composite particles created when airborne pollutants adsorb onto nanoplastics. The study employs advanced label-free imaging...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $419,375 under the Environmental Health program (CFDA 93.113) on August 10, 2026, to explore nanoplastics' neurological effects through investigation of lipid mechanisms and glial inflammation. The recipient will conduct research on micro- and nanoplastics bioaccumulation in the human brain and their molecular interactions within cerebrospinal fluid and the central nervous...
- The National Institute of Environmental Health Sciences awarded The University of Central Florida Board of Trustees $442,580 on September 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate microplastic-induced mechanobiological dysfunction in the vascular endothelium. The recipient will conduct a three-year study characterizing how microplastic exposure impairs endothelial cell mechanical integrity and function under physiologically relevant flow conditions. Aim 1...
- The Department of Agriculture National Institute of Food and Agriculture awarded Oklahoma State University $853,610 under the Agriculture and Food Research Initiative (AFRI) program on March 1, 2026, to investigate how microplastics in biosolids-derived fertilizers affect soil health and carbon cycling. The project uses laboratory testing to track microplastic movement and chemical transformation in soil following biosolids application, evaluates microplastic potential to alter soil carbon...
- The National Institute of Environmental Health Sciences awarded New Jersey Institute of Technology $759,977 for a Project Grant (R56ES037652) on September 1, 2026, under the Environmental Health program (CFDA 93.113). The award funds investigation of placental translocation and toxicity of environmentally relevant nanoplastics—plastic particles smaller than one micron that accumulate in human organs and may disrupt health during sensitive developmental windows. NJIT will study placental toxicity...
The National Institute of Environmental Health Sciences awarded Oklahoma State University $350,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the bioavailability and toxicity of microplastic and cadmium mixtures in the human gastrointestinal system and to develop undergraduate research training in interdisciplinary environmental science. The project examines how environmental weathering and digestive processes affect the sorption capacity, transformation, and toxicity of micro- and nanoplastics (MNPs) when co-exposed with cadmium and other contaminants. The work builds on findings from the prior 2022–2025 funding phase, which demonstrated that UV aging modifies polyethylene and polyvinyl chloride microplastics' capacity to adsorb cadmium and organic compounds, that MNPs attenuate cadmium bioavailability in vitro, and that nanoplastics increase toxicity in cellular assays. The renewal phase advances understanding of MNP transformation in the digestive system by recruiting and mentoring undergraduate students, supporting graduate researchers, and developing research skills in an interdisciplinary framework. Work is performed in Stillwater, Oklahoma. The period of performance runs from August 1, 2026, through July 31, 2029. This is a Project Grant, a form of assistance in which the federal government funds discrete, time-limited research activities at non-profit institutions. The funding mechanism supports investigator-initiated biomedical research of high scientific merit determined by peer review.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $350.0k | 7/31/26 |