Project Grant R01ES036962
- The University of Arizona received a $466,470 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), to investigate the impact of phthalate exposures on female reproduction and metabolism. The project aims to test the hypothesis that phthalate mixture exposure leads to stimulated fatty acid synthesis with concurrent inhibition of fatty acid oxidation, which may underlie the associations between...
- The National Institute of Environmental Health Sciences (NIEHS) awarded a $2,737,859 Project Grant (CFDA 93.113, Environmental Health) to the University of Illinois to conduct research on the "Impacts of Phthalate Exposure on the Development of Social Behavior Circuits". The 4-year award, running from September 2025 to September 2029, aims to investigate how exposure to phthalates, a class of endocrine-disrupting chemicals, during development can lead to alterations in brain...
- The National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) awarded a $1,999,075 Project Grant (CFDA 93.113 Environmental Health) to The Feinstein Institutes for Medical Research on September 1, 2023. The purpose of this 3-year grant is to investigate phthalate exposure and its mechanisms of action in the neonatal intensive care unit (NICU) environment. Specifically, the project aims to: 1) determine the pharmacokinetic profile of common phthalate...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113) provides $521,992 in funding to Midwestern University to investigate how exposure to phthalates during critical developmental windows can disrupt spermatogenesis through the disruption of LRH1 signaling in Sertoli cells. The two-year project, running from September 1, 2025 to August 31, 2028, aims to elucidate the molecular...
- This Project Grant award, with a total funding amount of $249,000.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The award will fund a research study at the University of North Carolina at Chapel Hill investigating the associations between prenatal exposure to phthalates and phthalate alternatives and fetal and pediatric cardiometabolic outcomes. The study will utilize innovative tools to...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will provide $719,892 to New York University to conduct research on the relationship between infant exposure to phthalates and bisphenols and reproductive development during the "minipuberty" period in the first six months of life. The project will enroll 480 infants in the ongoing NYU Children's Health and Environment...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $124,808.00 in funding to the University of Texas at Austin to investigate how exposure to environmental endocrine-disrupting chemicals (EDCs) impacts cognitive and food reward processes in the brain, with a focus on dopamine pathways. The research aims to explore the potential role of EDCs in the co-morbidity of obesity and...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $143,331 Project Grant to Wayne State University to investigate the molecular impacts of per- and polyfluoroalkyl substances (PFAS) exposure on male reproductive health. The research aims to use single-cell RNA sequencing and analysis of epididymal extracellular vesicles to decipher how PFAS exposure affects spermatogenesis, sperm epigenetics, and overall...
- This $126,970 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113) supports research to investigate the relationship between exposure to endocrine-disrupting chemicals (EDCs) and the development of metabolic syndrome (MetS) in a cohort of Hispanic women. The research aims to expand the principal investigator's expertise in environmental epidemiology and exposure-mixture analysis, as well as...
- This $756,318 federal Project Grant was awarded on June 3, 2025 by the National Institute of Environmental Health Sciences (NIEHS), a division of the U.S. National Institutes of Health (CFDA 93.113 Environmental Health). The grant supports research at Wayne State University to investigate how polyethoxylated surfactants, a class of emerging environmental contaminants, impact metabolic health and the development of obesity. The research will use zebrafish models to comprehensively assess the role...
The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $2,472,661 Project Grant to the Texas A&M University System Health Science Center (TAMU HSC) to investigate the effects of phthalate exposure on epigenetic regulation of metabolic pathways and the development of metabolic diseases. The 4-year project, commencing on September 15, 2025, aims to elucidate the mechanisms by which phthalates, a group of widely used plasticizers, can disrupt epigenetic processes and contribute to the increasing prevalence of metabolic disorders like type 2 diabetes and obesity. The research will focus on evaluating the impact of phthalate exposure on the epigenetic regulation of the SIRT3 gene, which plays a key role in metabolic syndrome. This work seeks to provide critical insights into how environmental chemical exposures can program fetal metabolic pathways through epigenetic mechanisms, with the goal of informing strategies to mitigate the public health consequences of the "diabesity" epidemic.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.5m | 9/12/25 |