This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) provides $308,799 to Stanford University to conduct research on the systemic benefits of exercise. The project aims to generate a comprehensive catalog of "exerkines" - molecules released during exercise that communicate between organs - and map their receptors across the body. The research will leverage the Molecular Transducers of Physical Activity Consortium (MoTrPAC) dataset, which profiles molecular changes in exercised rats, and cross-reference these findings with public datasets on healthy and diseased human tissues. The goal is to uncover overlapping pathways between exercise-induced signaling and disease dysregulation, providing insights into the mechanisms by which exercise can prevent and potentially reverse conditions such as cancer, cardiovascular disease, and neurodegenerative disorders. The project period is from June 10, 2025 to May 31, 2026.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $308.8k | 6/10/25 |