Project Grant R03HL180785
- The University of New Mexico was awarded a $522,990 Project Grant under the National Institutes of Health (NIH) National Heart, Lung, and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837). The grant, awarded on September 1, 2025, will support research to elucidate the mechanisms underlying the counter-regulation of allergic airway inflammation by regulating the responsiveness of Group 2 Innate Lymphoid Cells (ILC2s). The proposed studies aim to address the knowledge gap in...
- The Project Grant award of $673,581 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports a research project by Ochin, Inc. to assess disparities in asthma care between Latino and non-Hispanic white adults. The project aims to leverage a comprehensive dataset linking electronic health records to community-level social determinants of health data to evaluate factors underlying asthma care utilization disparities. The award runs from March 1, 2025...
- The National Heart, Lung, and Blood Institute (NHLBI), via the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $564,445 Project Grant to the University of Texas Health Science Center at Houston (UTHealth) to fund research on "Targeting Hypoxia-Inducible Factors (HIFs) for Heart and Lung Disease." The 6-year grant, starting on March 1, 2025 and ending on December 31, 2031, supports three complementary research projects focused on investigating the upstream regulation...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $106,391 to the University of Colorado-Denver to investigate the role of developmental dysanapsis in lung development over the lifespan in an experimental bronchopulmonary dysplasia (BPD) model. The research aims to determine whether intra-amniotic endotoxin causes persistent dysanaptic growth of the airways, distal parenchyma, and vasculature in BPD, and...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), supports research to investigate how early-life inflammation and viral infections shape the development and function of type 2 innate lymphoid cells (ILC2s) in the lungs, and their role in driving childhood asthma susceptibility. The $740,709 award to the University of Utah is intended to define the cellular and molecular mechanisms by...
- The University of Wisconsin System received a $176,220 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to investigate gene-by-air pollution interactions that may contribute to increased risk of preschool-onset childhood asthma among minority populations. The 5-year research project aims to: 1) conduct a candidate gene association study for preschool-onset asthma, 2) identify genetic variants that interact with early-life air...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $705,279 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to Trustees of Boston University, doing business as Boston University Medical Campus, to investigate the mechanisms by which environmental pollutants impact the cardiovascular system. The 4-year project, starting January 1, 2025, will use a multidisciplinary approach including physiological studies, cellular imaging, RNA-sequencing, and mouse models to...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $180,174 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The Children's Hospital of Philadelphia Research Institute. The grant will fund a study to develop a framework for designing the next generation of pediatric acute respiratory distress syndrome (ARDS) clinical trials. Key objectives include: 1) Comparing heterogeneity of treatment effect (HTE) analysis methodologies in a trial of pediatric...
- The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), awarded a $702,308 project grant to the University of Colorado-Denver for a study titled "Function and Regulation of Airway Mucin Glycosylation". The project, with a performance period from September 1, 2025 to June 30, 2029, aims to investigate the role of mucin glycosylation, specifically the enzyme fucosyltransferase 2 (FUT2), in regulating mucus...
- The Children's Hospital of Philadelphia (CHOP) received a $135,000 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) on July 16, 2025. The project aims to investigate how clinical, genetic, and social factors interact with short-term ambient air pollution (AAP) exposure to influence asthma exacerbations in pediatric patients. The research will also examine how these variables shape long-term lung function attainment in...
The National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), awarded a $189,000 Project Grant under CFDA #93.837 Cardiovascular Diseases Research program to the University of Colorado-Denver. The 2-year grant, with a period of performance from September 15, 2025 to August 31, 2027, will support research to investigate the role of outdoor air pollution and environmental allergens in driving treatment response in children with acute asthma exacerbations in the pediatric emergency department (ED). The research leverages clinical data and biosamples to determine the association between environmental factors and asthma exacerbation treatment responsiveness, with the goal of informing more precise ED treatment strategies for pediatric asthma.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $189.0k | 9/9/25 |