Project Grant K08HL173691
- The National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), awarded a $189,000 Project Grant under CFDA #93.837 Cardiovascular Diseases Research program to the University of Colorado-Denver. The 2-year grant, with a period of performance from September 15, 2025 to August 31, 2027, will support research to investigate the role of outdoor air pollution and environmental allergens in driving treatment response in children with acute asthma...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $3,082,011 to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research aimed at identifying gene-environment interactions with exposure to the air pollutant ozone that contribute to respiratory diseases like asthma and COPD. The project will utilize genetically diverse mouse populations as a discovery...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), provides $1,195,808 to the University of Wisconsin System to conduct research on the impact of the infant microbiome and its interactions with host genetics on the risk of childhood asthma. The key objectives of this award are to: (1) develop statistical methods to detect host genome-wide associations with the...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $246,000.00 to the University of Chicago to conduct research focused on understanding how the "farm effect" and early-life exposure to barn animals and microbes impacts the immune system and susceptibility to childhood asthma. The key products to be delivered through this 2-year project include: 1) a comprehensive characterization of the transcriptional...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, is supporting research to investigate the genetic mechanisms underlying maladaptive respiratory responses to air pollution, specifically ozone (O3) exposure. The $671,165 award, spanning January 1, 2025 to October 31, 2029, will enable researchers at the University of North Carolina at Chapel Hill to: Profile the transcriptomes and...
- The University of North Carolina at Chapel Hill (UNC-CH) was awarded a $120,756 Project Grant from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct research on identifying the genetic contributions to variations in ozone exposure response. The 3-year project, running from January 2025 to August 2027, will utilize primary human bronchial epithelial cell (HBEC) cultures to map expression quantitative trait loci (eQTL) associated with ozone...
- The Project Grant award of $673,581 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports a research project by Ochin, Inc. to assess disparities in asthma care between Latino and non-Hispanic white adults. The project aims to leverage a comprehensive dataset linking electronic health records to community-level social determinants of health data to evaluate factors underlying asthma care utilization disparities. The award runs from March 1, 2025...
- This $680,562 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research investigating the long-term lung epithelial alterations resulting from early-life respiratory syncytial virus (RSV) infection. The research aims to determine the mechanisms by which early-life RSV infection predisposes individuals to developing asthma later in life, focusing on the role of innate cytokines like IL-1β and IL-33 in driving...
- The federal Project Grant award of $732,225 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research on "Mitochondrial Mechanisms in Asthma" at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. This multi-year (2025-2029) project aims to investigate how variations in the mitochondrial genome influence asthma risk and pathophysiology through alterations in mitochondrial bioenergetics and...
- This $186,896 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will fund a study by the Regents of the University of California, San Francisco (UCSF) to examine the impact of adverse childhood experiences (ACEs) screening and behavioral-social support on asthma and chronic obstructive pulmonary disease (COPD) health outcomes. The study aims to leverage data from LADHS' implementation of ACEs screening to 1) analyze the...
The University of Wisconsin System received a $176,220 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to investigate gene-by-air pollution interactions that may contribute to increased risk of preschool-onset childhood asthma among minority populations. The 5-year research project aims to: 1) conduct a candidate gene association study for preschool-onset asthma, 2) identify genetic variants that interact with early-life air pollution exposure to increase asthma risk, and 3) analyze associations between air pollution exposure and expression of preschool-onset asthma genes. This research seeks to advance scientific understanding of the root causes of disproportionately high asthma rates in Black and Hispanic/Latino children.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $176.2k | 8/8/25 |